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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIGAR
All Species:
28.18
Human Site:
S228
Identified Species:
62
UniProt:
Q9NQ88
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ88
NP_065108.1
270
30063
S228
L
S
R
S
E
L
M
S
V
T
P
N
T
G
M
Chimpanzee
Pan troglodytes
XP_522324
270
30026
S228
L
S
R
S
E
L
M
S
V
T
P
N
T
G
I
Rhesus Macaque
Macaca mulatta
XP_001118082
270
29997
S228
L
R
R
S
E
V
M
S
V
T
P
N
T
G
M
Dog
Lupus familis
XP_543863
316
34501
L274
L
N
K
S
E
F
M
L
V
S
P
N
T
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZA9
269
29172
S228
R
D
K
L
E
L
S
S
I
T
P
N
T
G
I
Rat
Rattus norvegicus
NP_001020235
178
19233
S138
I
D
K
F
E
L
S
S
I
T
P
N
T
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518492
261
26811
A219
L
S
R
S
E
L
S
A
V
S
P
N
T
G
I
Chicken
Gallus gallus
XP_417232
280
30888
S232
L
T
K
T
Q
L
S
S
V
S
P
N
T
G
V
Frog
Xenopus laevis
Q4V7R0
275
30639
S228
L
K
K
S
R
E
L
S
V
S
P
N
T
G
I
Zebra Danio
Brachydanio rerio
Q29RA5
256
28162
S216
L
D
P
A
Q
Q
F
S
I
C
P
N
T
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784615
238
26671
S198
M
K
D
S
S
N
S
S
L
S
R
F
E
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.5
72.4
N.A.
72.2
43.7
N.A.
37.7
56
51.6
40.3
N.A.
N.A.
N.A.
N.A.
31.1
Protein Similarity:
100
99.2
98.1
77.8
N.A.
84.8
54.4
N.A.
51.4
72.8
68.3
58.1
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
93.3
86.6
60
N.A.
53.3
53.3
N.A.
73.3
53.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
80
N.A.
93.3
93.3
80
66.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
28
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
64
10
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
10
0
10
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
28
0
0
0
0
10
55
% I
% Lys:
0
19
46
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
73
0
0
10
0
55
10
10
10
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
37
0
0
0
0
0
0
0
28
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
91
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
91
0
0
0
0
% P
% Gln:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
37
0
10
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
28
0
64
10
0
46
82
0
46
0
0
0
0
0
% S
% Thr:
0
10
0
10
0
0
0
0
0
46
0
0
91
0
0
% T
% Val:
0
0
0
0
0
10
0
0
64
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _