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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf4
All Species:
22.12
Human Site:
S389
Identified Species:
40.56
UniProt:
Q9NQ89
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ89
NP_065107.1
552
63801
S389
K
L
K
E
S
L
D
S
G
N
Q
N
G
G
N
Chimpanzee
Pan troglodytes
XP_508940
621
71180
S458
K
L
K
E
S
L
D
S
G
N
Q
N
G
G
N
Rhesus Macaque
Macaca mulatta
XP_001100007
552
63923
S389
K
L
K
E
S
L
D
S
G
N
Q
N
G
G
N
Dog
Lupus familis
XP_534918
552
63791
S389
K
L
K
E
S
H
D
S
G
N
R
N
G
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91YN0
552
63626
S389
K
C
K
E
A
R
D
S
G
N
Q
N
G
G
S
Rat
Rattus norvegicus
NP_001100093
552
63601
S389
K
C
K
E
A
R
D
S
G
N
Q
N
G
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519711
242
28108
V93
D
A
V
K
S
G
R
V
E
L
H
Q
L
A
S
Chicken
Gallus gallus
XP_001231610
550
63170
H387
S
N
K
A
K
R
H
H
G
N
K
D
S
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071257
551
63335
E388
S
K
Q
R
E
Q
P
E
M
P
R
N
G
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651623
535
60552
T370
E
D
S
S
G
S
S
T
S
N
S
S
A
E
G
Honey Bee
Apis mellifera
XP_394347
551
62901
R381
V
K
D
A
V
A
W
R
Q
A
H
H
K
E
T
Nematode Worm
Caenorhab. elegans
NP_741631
547
62200
A385
E
E
T
S
K
L
I
A
E
G
K
T
P
P
E
Sea Urchin
Strong. purpuratus
XP_790292
626
71624
K462
A
R
R
K
D
K
K
K
L
S
G
G
G
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
99.2
97
N.A.
94.1
94
N.A.
34
83.8
N.A.
77.7
N.A.
35.3
41.8
27.7
42.1
Protein Similarity:
100
87.4
99.6
98.5
N.A.
97
96.9
N.A.
39.6
91.4
N.A.
89.4
N.A.
54.5
61.9
49.8
58.7
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
6.6
26.6
N.A.
26.6
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
20
40
N.A.
40
N.A.
26.6
6.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
16
8
0
8
0
8
0
0
8
8
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
8
0
47
0
0
0
0
8
0
0
0
% D
% Glu:
16
8
0
47
8
0
0
8
16
0
0
0
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
0
0
54
8
8
8
62
62
8
% G
% His:
0
0
0
0
0
8
8
8
0
0
16
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% I
% Lys:
47
16
54
16
16
8
8
8
0
0
16
0
8
8
0
% K
% Leu:
0
31
0
0
0
31
0
0
8
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
62
0
54
0
0
39
% N
% Pro:
0
0
0
0
0
0
8
0
0
8
0
0
8
8
0
% P
% Gln:
0
0
8
0
0
8
0
0
8
0
39
8
0
0
0
% Q
% Arg:
0
8
8
8
0
24
8
8
0
0
16
0
0
0
0
% R
% Ser:
16
0
8
16
39
8
8
47
8
8
8
8
8
0
24
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
8
% T
% Val:
8
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _