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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf4
All Species:
17.88
Human Site:
T66
Identified Species:
32.78
UniProt:
Q9NQ89
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ89
NP_065107.1
552
63801
T66
K
D
L
K
E
A
L
T
Q
F
I
E
E
E
S
Chimpanzee
Pan troglodytes
XP_508940
621
71180
T135
K
D
L
K
E
A
L
T
Q
F
I
E
E
E
S
Rhesus Macaque
Macaca mulatta
XP_001100007
552
63923
T66
K
D
L
K
E
A
L
T
Q
F
I
E
E
E
S
Dog
Lupus familis
XP_534918
552
63791
S66
K
D
L
K
E
A
L
S
Q
F
I
E
E
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91YN0
552
63626
S66
S
D
L
K
D
A
L
S
R
F
I
E
E
E
S
Rat
Rattus norvegicus
NP_001100093
552
63601
A66
N
D
L
K
E
A
L
A
R
F
I
E
E
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519711
242
28108
Chicken
Gallus gallus
XP_001231610
550
63170
N66
N
D
L
K
Q
S
L
N
K
F
I
E
D
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071257
551
63335
G66
T
D
L
K
N
R
L
G
S
F
I
E
S
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651623
535
60552
Q69
I
K
L
E
R
E
L
Q
K
F
V
D
T
E
Q
Honey Bee
Apis mellifera
XP_394347
551
62901
E64
S
D
L
L
K
S
L
E
N
T
I
K
T
F
T
Nematode Worm
Caenorhab. elegans
NP_741631
547
62200
E71
L
D
Y
E
G
A
K
E
A
L
R
K
F
I
Y
Sea Urchin
Strong. purpuratus
XP_790292
626
71624
V99
T
Y
S
M
A
E
C
V
S
H
A
P
N
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
99.2
97
N.A.
94.1
94
N.A.
34
83.8
N.A.
77.7
N.A.
35.3
41.8
27.7
42.1
Protein Similarity:
100
87.4
99.6
98.5
N.A.
97
96.9
N.A.
39.6
91.4
N.A.
89.4
N.A.
54.5
61.9
49.8
58.7
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
0
53.3
N.A.
53.3
N.A.
26.6
26.6
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
0
86.6
N.A.
60
N.A.
53.3
53.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
54
0
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
0
8
0
0
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
0
16
39
16
0
16
0
0
0
62
47
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
70
0
0
8
8
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
70
0
0
8
0
% I
% Lys:
31
8
0
62
8
0
8
0
16
0
0
16
0
0
8
% K
% Leu:
8
0
77
8
0
0
77
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
8
0
0
8
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
31
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
8
0
0
16
0
8
0
0
0
0
% R
% Ser:
16
0
8
0
0
16
0
16
16
0
0
0
8
0
47
% S
% Thr:
16
0
0
0
0
0
0
24
0
8
0
0
16
8
24
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _