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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO2 All Species: 16.67
Human Site: S988 Identified Species: 40.74
UniProt: Q9NQ90 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ90 NP_065106.2 1003 113969 S988 S S A P S G Q S Q L G S M M S
Chimpanzee Pan troglodytes XP_508944 999 113482 S984 G S A P S G Q S Q L G S M I S
Rhesus Macaque Macaca mulatta XP_001118212 1094 124416 S1032 S S A P S G Q S Q P G S S F P
Dog Lupus familis XP_854489 1037 118791 G1022 D E P C N N H G P K A C L D S
Cat Felis silvestris
Mouse Mus musculus Q8CFW1 1002 114116 S987 S S A P S G R S Q P G S I A S
Rat Rattus norvegicus Q6IFT6 860 97152 G846 L G A T G V K G E Q P P S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507078 891 103110 V877 I V F Q V L F V L R F L K I M
Chicken Gallus gallus XP_425659 1051 121644 S1036 S F S Q F N Q S Q K G S I V S
Frog Xenopus laevis NP_001128709 979 113207 S964 Q S P G L S R S Q R G S S S S
Zebra Danio Brachydanio rerio Q4V8U5 646 74505 L632 S K L D F E S L E A L K K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 82.8 56.5 N.A. 92 34.2 N.A. 55.4 67.6 56.4 22.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 85.5 71.1 N.A. 94.8 52.5 N.A. 68.3 76.7 71.8 37.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 73.3 6.6 N.A. 73.3 6.6 N.A. 0 46.6 40 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 73.3 20 N.A. 86.6 20 N.A. 6.6 66.6 46.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 0 0 0 0 10 10 0 0 10 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 0 0 0 10 0 0 20 0 0 0 0 0 10 % E
% Phe: 0 10 10 0 20 0 10 0 0 0 10 0 0 10 0 % F
% Gly: 10 10 0 10 10 40 0 20 0 0 60 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 20 20 0 % I
% Lys: 0 10 0 0 0 0 10 0 0 20 0 10 20 0 10 % K
% Leu: 10 0 10 0 10 10 0 10 10 20 10 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 10 % M
% Asn: 0 0 0 0 10 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 40 0 0 0 0 10 20 10 10 0 0 10 % P
% Gln: 10 0 0 20 0 0 40 0 60 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 20 0 0 20 0 0 0 10 0 % R
% Ser: 50 50 10 0 40 10 10 60 0 0 0 60 30 20 60 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 10 10 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _