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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
A1CF
All Species:
22.73
Human Site:
S274
Identified Species:
50
UniProt:
Q9NQ94
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ94
NP_055391.2
594
65202
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Chimpanzee
Pan troglodytes
XP_521478
594
65181
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Rhesus Macaque
Macaca mulatta
XP_001100059
592
65038
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Dog
Lupus familis
XP_534776
590
65058
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5YD48
595
65706
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Rat
Rattus norvegicus
Q923K9
594
65601
S274
D
Y
A
F
V
H
F
S
N
R
E
D
A
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506578
571
63729
R266
V
E
R
V
K
K
I
R
D
Y
A
F
V
H
F
Chicken
Gallus gallus
XP_421561
596
66287
N274
D
Y
A
F
V
H
F
N
K
R
E
D
A
V
H
Frog
Xenopus laevis
NP_001086049
584
64248
R274
D
Y
A
F
V
H
F
R
N
R
A
D
A
V
D
Zebra Danio
Brachydanio rerio
Q08BH5
510
56941
L211
W
A
E
P
E
K
E
L
D
E
E
T
M
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781163
595
65764
F276
D
F
A
F
I
H
F
F
T
R
E
D
A
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
95.6
N.A.
93.2
94.1
N.A.
73.4
83
81.6
44.9
N.A.
N.A.
N.A.
N.A.
54.2
Protein Similarity:
100
99.8
98.3
97.1
N.A.
95.8
96.4
N.A.
79.8
88.5
89.2
60.6
N.A.
N.A.
N.A.
N.A.
67.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
80
6.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
86.6
86.6
13.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
82
0
0
0
0
0
0
0
19
0
82
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
0
0
0
0
0
19
0
0
82
0
0
10
% D
% Glu:
0
10
10
0
10
0
10
0
0
10
82
0
0
0
55
% E
% Phe:
0
10
0
82
0
0
82
10
0
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
82
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
19
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
64
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
19
0
82
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% T
% Val:
10
0
0
10
73
0
0
0
0
0
0
0
10
73
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _