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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPV5 All Species: 21.82
Human Site: T691 Identified Species: 43.64
UniProt: Q9NQA5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQA5 NP_062815.2 729 82551 T691 P T S S L S R T A S Q S S S H
Chimpanzee Pan troglodytes XP_519444 729 82502 T691 P T S S L S R T A S Q S S S H
Rhesus Macaque Macaca mulatta XP_001089988 729 82599 T691 P N S S L S R T T S Q S S S H
Dog Lupus familis XP_539860 808 91760 T769 P T P S L S R T T S H S S S H
Cat Felis silvestris
Mouse Mus musculus P69744 723 82199 T684 Q T P P L S R T T S L S S N S
Rat Rattus norvegicus Q9JIP0 723 82435 T684 Q T P P L S R T T S L S S N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518104 356 39437 T319 R L V G E L L T V V G A V A I
Chicken Gallus gallus XP_416530 724 82934 K678 D R N I L Y K K D L S I P S L
Frog Xenopus laevis NP_001082336 674 75844 P636 E L E G S R A P M A Q R R S S
Zebra Danio Brachydanio rerio NP_001001849 707 80910 S668 S K S D G E Q S I T E S N K E
Tiger Blowfish Takifugu rubipres NP_001027938 719 81679 T682 T Q F G L K T T E S L N R K S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6AWW5 524 56905 M487 M V S T L G T M C Y W V I A N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.8 78.4 N.A. 80.6 79.9 N.A. 34.7 68.7 50.8 46.9 51.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98 83.2 N.A. 88.8 89 N.A. 40.5 82.9 66.6 68.5 69.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 80 N.A. 53.3 53.3 N.A. 6.6 13.3 13.3 13.3 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 80 N.A. 60 60 N.A. 20 26.6 20 46.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 17 9 0 9 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 9 0 9 0 9 9 0 0 9 0 9 0 0 0 9 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 25 9 9 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 34 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 0 9 9 0 9 % I
% Lys: 0 9 0 0 0 9 9 9 0 0 0 0 0 17 0 % K
% Leu: 0 17 0 0 75 9 9 0 0 9 25 0 0 0 9 % L
% Met: 9 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 0 0 0 0 0 0 9 9 17 9 % N
% Pro: 34 0 25 17 0 0 0 9 0 0 0 0 9 0 0 % P
% Gln: 17 9 0 0 0 0 9 0 0 0 34 0 0 0 0 % Q
% Arg: 9 9 0 0 0 9 50 0 0 0 0 9 17 0 0 % R
% Ser: 9 0 42 34 9 50 0 9 0 59 9 59 50 50 34 % S
% Thr: 9 42 0 9 0 0 17 67 34 9 0 0 0 0 0 % T
% Val: 0 9 9 0 0 0 0 0 9 9 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _