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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPV5
All Species:
16.67
Human Site:
Y647
Identified Species:
33.33
UniProt:
Q9NQA5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQA5
NP_062815.2
729
82551
Y647
N
P
L
R
V
L
R
Y
V
E
V
F
K
N
S
Chimpanzee
Pan troglodytes
XP_519444
729
82502
Y647
N
P
L
R
V
L
R
Y
L
E
V
F
K
N
S
Rhesus Macaque
Macaca mulatta
XP_001089988
729
82599
Y647
N
P
L
R
V
L
R
Y
V
E
A
F
K
N
S
Dog
Lupus familis
XP_539860
808
91760
E725
L
R
V
L
R
Y
V
E
A
F
K
G
S
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P69744
723
82199
Y640
N
P
Y
R
V
L
R
Y
V
E
A
F
K
S
S
Rat
Rattus norvegicus
Q9JIP0
723
82435
Y640
N
P
Y
R
V
L
R
Y
V
E
A
F
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518104
356
39437
I275
V
C
F
T
M
C
C
I
Y
R
P
L
K
P
K
Chicken
Gallus gallus
XP_416530
724
82934
R634
L
G
D
R
W
Y
L
R
I
E
D
R
I
D
P
Frog
Xenopus laevis
NP_001082336
674
75844
D592
L
C
V
K
E
T
Q
D
P
Q
K
I
I
F
P
Zebra Danio
Brachydanio rerio
NP_001001849
707
80910
E624
G
L
M
F
G
L
G
E
R
W
Y
L
R
V
E
Tiger Blowfish
Takifugu rubipres
NP_001027938
719
81679
D638
R
W
Y
L
R
V
E
D
R
N
D
P
L
F
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6AWW5
524
56905
W443
A
I
I
N
K
L
M
W
M
A
C
I
M
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
78.4
N.A.
80.6
79.9
N.A.
34.7
68.7
50.8
46.9
51.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98
83.2
N.A.
88.8
89
N.A.
40.5
82.9
66.6
68.5
69.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
80
80
N.A.
6.6
13.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
86.6
86.6
N.A.
13.3
26.6
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
9
9
25
0
0
0
0
% A
% Cys:
0
17
0
0
0
9
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
17
0
0
17
0
0
17
0
% D
% Glu:
0
0
0
0
9
0
9
17
0
50
0
0
0
0
9
% E
% Phe:
0
0
9
9
0
0
0
0
0
9
0
42
0
17
0
% F
% Gly:
9
9
0
0
9
0
9
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
9
9
0
0
17
17
9
0
% I
% Lys:
0
0
0
9
9
0
0
0
0
0
17
0
50
0
17
% K
% Leu:
25
9
25
17
0
59
9
0
9
0
0
17
9
0
0
% L
% Met:
0
0
9
0
9
0
9
0
9
0
0
0
9
0
0
% M
% Asn:
42
0
0
9
0
0
0
0
0
9
0
0
0
25
0
% N
% Pro:
0
42
0
0
0
0
0
0
9
0
9
9
0
9
17
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% Q
% Arg:
9
9
0
50
17
0
42
9
17
9
0
9
9
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
50
% S
% Thr:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
17
0
42
9
9
0
34
0
17
0
0
9
0
% V
% Trp:
0
9
0
0
9
0
0
9
0
9
0
0
0
0
0
% W
% Tyr:
0
0
25
0
0
17
0
42
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _