Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF15 All Species: 23.33
Human Site: S117 Identified Species: 42.78
UniProt: Q9NQC1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQC1 NP_056103.4 790 87466 S117 E G P P A Q A S P S S T M L G
Chimpanzee Pan troglodytes XP_517936 825 91312 S117 E G P P A Q A S P S S T T L G
Rhesus Macaque Macaca mulatta XP_001102649 834 92117 S117 E G P P V Q A S P S S T T L G
Dog Lupus familis XP_850716 782 86718 S115 E G P P T Q V S P S S S E L G
Cat Felis silvestris
Mouse Mus musculus Q6ZQF7 829 92156 S117 K G P P T Q M S P D S P T L G
Rat Rattus norvegicus NP_001100468 829 92107 S117 K G P P T L M S P E S P T L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518425 406 45614
Chicken Gallus gallus XP_414632 797 89313 S117 P S P V S P S S L Q G S E I S
Frog Xenopus laevis Q6GQJ2 827 94374 S118 K Y I H S S G S E P P E V G Y
Zebra Danio Brachydanio rerio Q803A0 829 94529 S114 P K K L I R S S E S S M L G Y
Tiger Blowfish Takifugu rubipres NP_001041504 790 88254 Q120 K Y I Q S S N Q E S T E P G F
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20318 1042 117625 P115 G M P L Q K F P E F K H D H E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12311 748 86011 S118 R F N E S F I S R Y Y H I N K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.4 94.1 93.4 N.A. 87 86.4 N.A. 39.6 70.3 46.4 44.1 45 N.A. N.A. 20.4 N.A.
Protein Similarity: 100 86.3 94.1 94.9 N.A. 89.6 88.9 N.A. 44.8 76.6 60.2 57.5 58.7 N.A. N.A. 35.7 N.A.
P-Site Identity: 100 93.3 86.6 73.3 N.A. 60 53.3 N.A. 0 13.3 6.6 20 6.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 86.6 80 N.A. 66.6 60 N.A. 0 40 26.6 40 26.6 N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 24 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 31 0 0 8 0 0 0 0 31 8 0 16 16 0 8 % E
% Phe: 0 8 0 0 0 8 8 0 0 8 0 0 0 0 8 % F
% Gly: 8 47 0 0 0 0 8 0 0 0 8 0 0 24 47 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 16 0 8 0 % H
% Ile: 0 0 16 0 8 0 8 0 0 0 0 0 8 8 0 % I
% Lys: 31 8 8 0 0 8 0 0 0 0 8 0 0 0 8 % K
% Leu: 0 0 0 16 0 8 0 0 8 0 0 0 8 47 0 % L
% Met: 0 8 0 0 0 0 16 0 0 0 0 8 8 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % N
% Pro: 16 0 62 47 0 8 0 8 47 8 8 16 8 0 0 % P
% Gln: 0 0 0 8 8 39 0 8 0 8 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 31 16 16 77 0 47 54 16 0 0 8 % S
% Thr: 0 0 0 0 24 0 0 0 0 0 8 24 31 0 0 % T
% Val: 0 0 0 8 8 0 8 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 0 0 0 0 8 8 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _