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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HINT3
All Species:
9.09
Human Site:
T61
Identified Species:
15.38
UniProt:
Q9NQE9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQE9
NP_612638.3
182
20361
T61
A
G
R
Q
D
P
G
T
E
L
L
H
C
E
N
Chimpanzee
Pan troglodytes
XP_001165850
182
20357
T61
A
G
R
Q
D
P
G
T
E
L
L
H
C
E
N
Rhesus Macaque
Macaca mulatta
XP_001107408
182
20374
T61
A
G
Q
Q
D
P
G
T
E
L
L
Y
C
E
N
Dog
Lupus familis
XP_533489
139
16007
D27
F
K
R
G
S
N
E
D
L
V
C
F
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPS6
165
18769
D53
L
F
H
C
E
N
E
D
L
V
C
F
K
D
I
Rat
Rattus norvegicus
Q8K3P7
175
19675
E60
E
T
E
L
L
Y
C
E
N
K
D
L
V
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506814
184
20799
P63
G
S
E
A
A
P
D
P
P
Y
E
E
L
V
C
Chicken
Gallus gallus
XP_001232866
167
18581
R55
Y
E
D
L
V
C
F
R
D
I
R
P
G
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PNN8
160
18444
F48
E
D
E
D
F
V
C
F
R
D
I
N
P
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001033848
139
15898
D27
V
L
E
V
E
N
D
D
F
V
I
F
Q
D
I
Honey Bee
Apis mellifera
XP_625181
140
16403
V28
K
I
Y
E
D
N
Y
V
T
C
I
K
D
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187365
104
11822
Poplar Tree
Populus trichocarpa
XP_002304274
147
16751
I35
K
V
V
A
F
Q
D
I
N
P
S
A
F
R
H
Maize
Zea mays
NP_001151003
168
19021
N56
V
V
A
F
R
D
I
N
P
S
A
F
R
H
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
62
N.A.
64.2
64.8
N.A.
50
55.4
N.A.
39
N.A.
30.7
28
N.A.
26.3
Protein Similarity:
100
99.4
97.8
68.1
N.A.
76.9
80.2
N.A.
61.9
73
N.A.
57.1
N.A.
45.5
46.7
N.A.
37.3
P-Site Identity:
100
100
86.6
6.6
N.A.
0
0
N.A.
6.6
0
N.A.
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
20
0
N.A.
6.6
13.3
N.A.
13.3
N.A.
26.6
26.6
N.A.
0
Percent
Protein Identity:
32.9
33.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
48.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
15
8
0
0
0
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
8
0
8
15
0
0
8
15
0
22
8
8
% C
% Asp:
0
8
8
8
29
8
22
22
8
8
8
0
8
22
0
% D
% Glu:
15
8
29
8
15
0
15
8
22
0
8
8
0
22
0
% E
% Phe:
8
8
0
8
15
0
8
8
8
0
0
29
8
0
8
% F
% Gly:
8
22
0
8
0
0
22
0
0
0
0
0
8
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
15
0
8
15
% H
% Ile:
0
8
0
0
0
0
8
8
0
8
22
0
0
8
22
% I
% Lys:
15
8
0
0
0
0
0
0
0
8
0
8
15
0
0
% K
% Leu:
8
8
0
15
8
0
0
0
15
22
22
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
29
0
8
15
0
0
8
0
0
22
% N
% Pro:
0
0
0
0
0
29
0
8
15
8
0
8
8
0
8
% P
% Gln:
0
0
8
22
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
22
0
8
0
0
8
8
0
8
0
8
8
0
% R
% Ser:
0
8
0
0
8
0
0
0
0
8
8
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
22
8
0
0
0
0
0
0
% T
% Val:
15
15
8
8
8
8
0
8
0
22
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
8
0
0
8
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _