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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HINT3
All Species:
10.91
Human Site:
Y44
Identified Species:
18.46
UniProt:
Q9NQE9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQE9
NP_612638.3
182
20361
Y44
K
S
P
E
P
K
D
Y
D
S
T
C
V
F
C
Chimpanzee
Pan troglodytes
XP_001165850
182
20357
Y44
K
S
P
E
P
K
D
Y
D
S
T
C
V
F
C
Rhesus Macaque
Macaca mulatta
XP_001107408
182
20374
Y44
K
S
P
E
P
K
D
Y
D
S
T
C
V
F
C
Dog
Lupus familis
XP_533489
139
16007
L10
M
K
K
A
E
K
H
L
K
S
N
N
G
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPS6
165
18769
V36
S
N
C
V
F
C
R
V
A
A
G
Q
E
P
K
Rat
Rattus norvegicus
Q8K3P7
175
19675
F43
D
Y
D
S
N
C
V
F
C
R
V
A
A
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506814
184
20799
R46
A
L
P
V
R
P
R
R
R
T
P
P
E
S
W
Chicken
Gallus gallus
XP_001232866
167
18581
E38
C
R
I
A
R
R
E
E
P
G
T
A
L
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PNN8
160
18444
G31
I
F
C
T
I
A
K
G
D
D
R
Y
T
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001033848
139
15898
L10
D
D
N
C
I
F
C
L
I
S
D
G
R
I
P
Honey Bee
Apis mellifera
XP_625181
140
16403
D11
R
T
S
C
I
F
C
D
I
I
N
N
K
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187365
104
11822
Poplar Tree
Populus trichocarpa
XP_002304274
147
16751
S18
C
Q
I
A
T
K
S
S
S
T
T
L
L
H
S
Maize
Zea mays
NP_001151003
168
19021
T39
V
R
G
A
P
A
S
T
T
A
L
L
Y
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
62
N.A.
64.2
64.8
N.A.
50
55.4
N.A.
39
N.A.
30.7
28
N.A.
26.3
Protein Similarity:
100
99.4
97.8
68.1
N.A.
76.9
80.2
N.A.
61.9
73
N.A.
57.1
N.A.
45.5
46.7
N.A.
37.3
P-Site Identity:
100
100
100
13.3
N.A.
0
0
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
6.6
N.A.
13.3
26.6
N.A.
6.6
N.A.
6.6
13.3
N.A.
0
Percent
Protein Identity:
32.9
33.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
48.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
29
0
15
0
0
8
15
0
15
8
0
0
% A
% Cys:
15
0
15
15
0
15
15
0
8
0
0
22
0
0
22
% C
% Asp:
15
8
8
0
0
0
22
8
29
8
8
0
0
0
8
% D
% Glu:
0
0
0
22
8
0
8
8
0
0
0
0
15
15
0
% E
% Phe:
0
8
0
0
8
15
0
8
0
0
0
0
0
22
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
8
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
15
0
% H
% Ile:
8
0
15
0
22
0
0
0
15
8
0
0
0
8
8
% I
% Lys:
22
8
8
0
0
36
8
0
8
0
0
0
8
0
8
% K
% Leu:
0
8
0
0
0
0
0
15
0
0
8
15
15
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
0
15
15
0
0
8
% N
% Pro:
0
0
29
0
29
8
0
0
8
0
8
8
0
8
22
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
8
15
0
0
15
8
15
8
8
8
8
0
8
0
0
% R
% Ser:
8
22
8
8
0
0
15
8
8
36
0
0
0
15
8
% S
% Thr:
0
8
0
8
8
0
0
8
8
15
36
0
8
0
0
% T
% Val:
8
0
0
15
0
0
8
8
0
0
8
0
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
0
22
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _