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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HINT3
All Species:
18.48
Human Site:
Y85
Identified Species:
31.28
UniProt:
Q9NQE9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQE9
NP_612638.3
182
20361
Y85
K
P
A
A
T
H
H
Y
L
V
V
P
K
K
H
Chimpanzee
Pan troglodytes
XP_001165850
182
20357
Y85
K
P
A
A
T
H
H
Y
L
V
V
P
K
K
H
Rhesus Macaque
Macaca mulatta
XP_001107408
182
20374
Y85
K
P
A
A
T
H
H
Y
L
V
V
P
K
K
H
Dog
Lupus familis
XP_533489
139
16007
V45
A
P
H
H
Y
L
V
V
P
K
K
H
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPS6
165
18769
V71
A
L
Y
H
Y
L
V
V
P
K
K
H
I
G
S
Rat
Rattus norvegicus
Q8K3P7
175
19675
Y78
K
P
A
A
L
H
H
Y
L
V
V
P
K
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506814
184
20799
Y82
R
P
G
A
P
H
H
Y
L
V
V
P
K
K
H
Chicken
Gallus gallus
XP_001232866
167
18581
M73
L
V
V
P
V
E
H
M
G
N
C
K
T
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PNN8
160
18444
H66
Y
L
V
I
P
K
K
H
I
Y
S
C
L
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001033848
139
15898
V45
S
Q
H
H
Y
L
A
V
T
K
K
H
Y
A
S
Honey Bee
Apis mellifera
XP_625181
140
16403
P46
T
H
H
Y
L
I
L
P
K
E
H
I
R
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187365
104
11822
I10
A
A
C
V
F
H
D
I
R
P
S
T
K
E
H
Poplar Tree
Populus trichocarpa
XP_002304274
147
16751
T53
I
P
V
E
H
I
P
T
V
N
D
L
Q
K
R
Maize
Zea mays
NP_001151003
168
19021
V74
P
I
D
H
I
P
T
V
N
S
L
R
K
T
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95
62
N.A.
64.2
64.8
N.A.
50
55.4
N.A.
39
N.A.
30.7
28
N.A.
26.3
Protein Similarity:
100
99.4
97.8
68.1
N.A.
76.9
80.2
N.A.
61.9
73
N.A.
57.1
N.A.
45.5
46.7
N.A.
37.3
P-Site Identity:
100
100
100
6.6
N.A.
0
93.3
N.A.
80
6.6
N.A.
0
N.A.
0
0
N.A.
20
P-Site Similarity:
100
100
100
13.3
N.A.
0
93.3
N.A.
86.6
6.6
N.A.
13.3
N.A.
0
6.6
N.A.
26.6
Percent
Protein Identity:
32.9
33.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
48.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
29
36
0
0
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
8
0
8
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
8
0
0
0
0
15
0
% G
% His:
0
8
22
29
8
43
43
8
0
0
8
22
0
0
43
% H
% Ile:
8
8
0
8
8
15
0
8
8
0
0
8
8
0
0
% I
% Lys:
29
0
0
0
0
8
8
0
8
22
22
8
50
43
15
% K
% Leu:
8
15
0
0
15
22
8
0
36
0
8
8
15
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
15
0
0
0
8
8
% N
% Pro:
8
50
0
8
15
8
8
8
15
8
0
36
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
8
8
0
8
% R
% Ser:
8
0
0
0
0
0
0
0
0
8
15
0
0
8
15
% S
% Thr:
8
0
0
0
22
0
8
8
8
0
0
8
8
8
0
% T
% Val:
0
8
22
8
8
0
15
29
8
36
36
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
8
22
0
0
36
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _