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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MANBAL All Species: 26.06
Human Site: S59 Identified Species: 63.7
UniProt: Q9NQG1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQG1 NP_001003897.1 85 9467 S59 A E P S E P R S A E V T R K P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109329 85 9450 S59 A E P S E P R S A D V T R K P
Dog Lupus familis XP_852926 85 9396 S59 A E P S E P R S A E V T R K P
Cat Felis silvestris
Mouse Mus musculus Q9D8X0 85 9321 S59 A E Q A E P R S A E G P K K P
Rat Rattus norvegicus NP_001166851 85 9450 S59 A E P S E P R S A E V P K K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507781 181 18961 S121 P G A E A G R S A V L S G R E
Chicken Gallus gallus
Frog Xenopus laevis NP_001165192 85 9392 S59 S D S Q E V K S P E A V K K P
Zebra Danio Brachydanio rerio XP_001333294 88 9918 S62 S D P A D T R S T D Q N R K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77286 87 9611 G61 G Q S N P E S G E V T E R E G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199886 80 8944 T54 L Q E T A A E T D D I D V A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 88.2 90.5 N.A. 89.4 92.9 N.A. 29.2 N.A. 57.6 60.2 N.A. 28.7 N.A. N.A. 29.4
Protein Similarity: 100 N.A. 95.2 92.9 N.A. 92.9 95.2 N.A. 40.3 N.A. 70.5 77.2 N.A. 52.8 N.A. N.A. 56.4
P-Site Identity: 100 N.A. 93.3 100 N.A. 66.6 86.6 N.A. 20 N.A. 33.3 33.3 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 80 93.3 N.A. 40 N.A. 60 66.6 N.A. 26.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 10 20 20 10 0 0 60 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 10 0 0 0 10 30 0 10 0 0 0 % D
% Glu: 0 50 10 10 60 10 10 0 10 50 0 10 0 10 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 10 0 10 0 0 10 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 30 70 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 50 0 10 50 0 0 10 0 0 20 0 0 60 % P
% Gln: 0 20 10 10 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 70 0 0 0 0 0 50 10 0 % R
% Ser: 20 0 20 40 0 0 10 80 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 10 0 10 0 10 10 0 10 30 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 20 40 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _