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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPRD1B All Species: 25.45
Human Site: S171 Identified Species: 43.08
UniProt: Q9NQG5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQG5 NP_067038.1 326 36900 S171 S Y S P Q D P S A G P L L T E
Chimpanzee Pan troglodytes XP_001143572 314 35607 S161 S Y S P Q D P S A G P L L E L
Rhesus Macaque Macaca mulatta XP_001090633 314 35593 S161 S Y S P Q D P S A G P L L E L
Dog Lupus familis XP_542990 477 52007 S322 S Y S P Q D P S A G P L L T E
Cat Felis silvestris
Mouse Mus musculus Q9CSU0 326 36865 S171 S Y S P Q D P S A G P L L T E
Rat Rattus norvegicus NP_001092197 326 36865 S171 S Y S P Q D P S A G P L L T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512622 400 45577 P249 L G S P S D P P Q T T D L T R
Chicken Gallus gallus Q5ZM30 268 30818 D120 E R S V Y E N D V L E Q L R Q
Frog Xenopus laevis NP_001086593 325 36801 S170 S Y S P Q E T S T G P L L T E
Zebra Danio Brachydanio rerio NP_955850 335 38090 A180 Y S P R E T D A A A P Q L T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396379 332 37569 A177 T L S P R T P A G D P P E T E
Nematode Worm Caenorhab. elegans P34281 315 36355 E162 Q P S Q F V V E E A K K N A Q
Sea Urchin Strong. purpuratus XP_779930 352 40189 I196 E E E E L Q Q I E D M P D P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05543 409 46470 H162 E K L V K M H H N V C A M K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 95.4 68.3 N.A. 99.3 99.3 N.A. 53.7 54.5 84.3 79.4 N.A. N.A. 54.8 24.5 50.2
Protein Similarity: 100 95.4 96.3 68.3 N.A. 99.6 99.6 N.A. 65.2 70.5 92.6 90.4 N.A. N.A. 71.6 46.6 68.4
P-Site Identity: 100 86.6 86.6 100 N.A. 100 100 N.A. 40 13.3 80 33.3 N.A. N.A. 40 6.6 0
P-Site Similarity: 100 86.6 86.6 100 N.A. 100 100 N.A. 40 26.6 86.6 46.6 N.A. N.A. 60 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 50 15 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 50 8 8 0 15 0 8 8 0 8 % D
% Glu: 22 8 8 8 8 15 0 8 15 0 8 0 8 15 50 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 50 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 8 0 0 0 0 0 8 8 0 8 0 % K
% Leu: 8 8 8 0 8 0 0 0 0 8 0 50 72 0 15 % L
% Met: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 8 % M
% Asn: 0 0 0 0 0 0 8 0 8 0 0 0 8 0 0 % N
% Pro: 0 8 8 65 0 0 58 8 0 0 65 15 0 8 0 % P
% Gln: 8 0 0 8 50 8 8 0 8 0 0 15 0 0 15 % Q
% Arg: 0 8 0 8 8 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 50 8 79 0 8 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 15 8 0 8 8 8 0 0 58 0 % T
% Val: 0 0 0 15 0 8 8 0 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 50 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _