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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPRD1B All Species: 6.36
Human Site: T140 Identified Species: 10.77
UniProt: Q9NQG5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQG5 NP_067038.1 326 36900 T140 K S P P P K A T E E K K S L K
Chimpanzee Pan troglodytes XP_001143572 314 35607 W130 Q Q L K L Q A W G Q K K S L K
Rhesus Macaque Macaca mulatta XP_001090633 314 35593 K130 Q Q L K L A L K E D K K S L K
Dog Lupus familis XP_542990 477 52007 T291 K S P P P K A T E E K K S L K
Cat Felis silvestris
Mouse Mus musculus Q9CSU0 326 36865 A140 K S P P P K A A E E K K S L K
Rat Rattus norvegicus NP_001092197 326 36865 A140 K S P P P K A A E E K K S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512622 400 45577 Y218 E Q L R H A L Y G E K K S R K
Chicken Gallus gallus Q5ZM30 268 30818 F89 A P V I V E A F K H V S S E S
Frog Xenopus laevis NP_001086593 325 36801 P139 D D S P R E A P V N E E K S L
Zebra Danio Brachydanio rerio NP_955850 335 38090 K149 Q R N A D D R K N L K R S Y Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396379 332 37569 N146 P P K K K L K N D I E K E R K
Nematode Worm Caenorhab. elegans P34281 315 36355 H131 C K R L H E V H Q Q V K L S G
Sea Urchin Strong. purpuratus XP_779930 352 40189 Q165 K E S K R E Q Q E E E E S T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05543 409 46470 L131 V N D I E R S L K T E S S P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 95.4 68.3 N.A. 99.3 99.3 N.A. 53.7 54.5 84.3 79.4 N.A. N.A. 54.8 24.5 50.2
Protein Similarity: 100 95.4 96.3 68.3 N.A. 99.6 99.6 N.A. 65.2 70.5 92.6 90.4 N.A. N.A. 71.6 46.6 68.4
P-Site Identity: 100 40 40 100 N.A. 93.3 93.3 N.A. 33.3 13.3 13.3 13.3 N.A. N.A. 13.3 6.6 26.6
P-Site Similarity: 100 60 53.3 100 N.A. 93.3 93.3 N.A. 40 26.6 33.3 33.3 N.A. N.A. 26.6 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 15 50 15 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 8 8 0 0 8 8 0 0 0 0 0 % D
% Glu: 8 8 0 0 8 29 0 0 43 43 29 15 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 8 % G
% His: 0 0 0 0 15 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 15 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 36 8 8 29 8 29 8 15 15 0 58 65 8 0 58 % K
% Leu: 0 0 22 8 15 8 15 8 0 8 0 0 8 43 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 8 15 29 36 29 0 0 8 0 0 0 0 0 8 8 % P
% Gln: 22 22 0 0 0 8 8 8 8 15 0 0 0 0 8 % Q
% Arg: 0 8 8 8 15 8 8 0 0 0 0 8 0 15 0 % R
% Ser: 0 29 15 0 0 0 8 0 0 0 0 15 79 15 8 % S
% Thr: 0 0 0 0 0 0 0 15 0 8 0 0 0 8 0 % T
% Val: 8 0 8 0 8 0 8 0 8 0 15 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _