KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMCR7L
All Species:
18.18
Human Site:
T89
Identified Species:
40
UniProt:
Q9NQG6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQG6
NP_061881.2
463
51293
T89
L
L
N
R
D
M
K
T
G
L
S
R
S
L
Q
Chimpanzee
Pan troglodytes
XP_001165349
463
51235
T89
L
L
N
R
D
M
K
T
G
L
S
R
S
L
Q
Rhesus Macaque
Macaca mulatta
XP_001098078
463
51253
T89
L
L
N
R
D
M
K
T
G
L
S
R
S
L
Q
Dog
Lupus familis
XP_852489
463
51255
T89
L
L
N
K
D
M
K
T
G
L
S
R
S
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGV8
463
51166
A89
L
L
N
K
D
M
K
A
G
L
S
R
S
L
Q
Rat
Rattus norvegicus
Q5XIS8
463
51291
T89
L
L
N
R
D
M
K
T
G
L
S
R
S
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518534
276
30405
Chicken
Gallus gallus
XP_416248
464
51575
K89
R
L
L
S
Q
D
M
K
T
N
L
S
R
S
L
Frog
Xenopus laevis
Q6GQ81
463
51973
R90
K
A
S
P
T
L
R
R
K
E
D
L
E
H
H
Zebra Danio
Brachydanio rerio
A4IG61
468
52083
K90
R
T
L
N
H
D
M
K
Q
N
V
S
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01908
373
40893
L24
L
S
A
D
S
S
S
L
S
F
R
S
V
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
98
N.A.
97.8
98
N.A.
53.3
86.2
44.4
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.3
99.3
N.A.
99.3
99.3
N.A.
55.9
92.4
61.3
83.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
100
N.A.
0
6.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
0
6.6
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
55
19
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
19
0
0
55
19
10
0
0
0
0
0
10
% K
% Leu:
64
64
19
0
0
10
0
10
0
55
10
10
0
64
19
% L
% Met:
0
0
0
0
0
55
19
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
55
10
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
55
% Q
% Arg:
19
0
0
37
0
0
10
10
0
0
10
55
19
0
0
% R
% Ser:
0
10
10
10
10
10
10
0
10
0
55
28
55
19
0
% S
% Thr:
0
10
0
0
10
0
0
46
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _