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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPS4
All Species:
9.09
Human Site:
T298
Identified Species:
25
UniProt:
Q9NQG7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQG7
NP_071364.4
708
76919
T298
S
A
L
K
E
N
A
T
G
H
V
E
S
M
A
Chimpanzee
Pan troglodytes
XP_001171982
708
76939
T298
S
A
L
K
E
N
A
T
G
H
V
E
S
M
A
Rhesus Macaque
Macaca mulatta
XP_001099509
708
76900
T298
S
A
L
K
E
N
A
T
G
H
V
E
S
M
A
Dog
Lupus familis
XP_543456
712
77450
I298
A
A
P
T
E
N
A
I
G
H
M
E
P
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99KG7
671
72644
P277
Q
G
S
S
V
Q
Y
P
P
W
D
Q
S
S
P
Rat
Rattus norvegicus
NP_001100618
312
33237
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415198
546
60260
K152
K
S
T
D
D
L
H
K
I
F
N
S
L
W
N
Frog
Xenopus laevis
NP_001088600
620
68706
G226
Q
F
P
V
S
E
D
G
T
Q
E
G
I
T
G
Zebra Danio
Brachydanio rerio
NP_956620
647
71917
N253
Y
L
T
P
S
E
L
N
M
I
R
S
P
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
93
70.6
N.A.
62.4
33.1
N.A.
N.A.
49
38.8
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95
78.7
N.A.
71.8
36.5
N.A.
N.A.
59.5
53.2
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
6.6
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
0
N.A.
N.A.
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
45
0
0
0
0
45
0
0
0
0
0
0
0
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
12
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
45
23
0
0
0
0
12
45
0
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
12
45
0
0
12
0
0
12
% G
% His:
0
0
0
0
0
0
12
0
0
45
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
12
12
0
0
12
0
0
% I
% Lys:
12
0
0
34
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
12
34
0
0
12
12
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
12
0
0
45
0
% M
% Asn:
0
0
0
0
0
45
0
12
0
0
12
0
0
0
12
% N
% Pro:
0
0
23
12
0
0
0
12
12
0
0
0
23
12
12
% P
% Gln:
23
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
34
12
12
12
23
0
0
0
0
0
0
23
45
12
0
% S
% Thr:
0
0
23
12
0
0
0
34
12
0
0
0
0
12
0
% T
% Val:
0
0
0
12
12
0
0
0
0
0
34
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% W
% Tyr:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _