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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX4 All Species: 6.67
Human Site: S164 Identified Species: 10.48
UniProt: Q9NQI0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQI0 NP_001129506.1 724 79308 S164 R G G F G L G S P N N D L D P
Chimpanzee Pan troglodytes Q6GVM6 660 73172 R143 K P L P P S E R L E Q E L F S
Rhesus Macaque Macaca mulatta XP_001100045 725 79200 S165 R G G F G L G S P N N D L D P
Dog Lupus familis XP_544339 725 79354 N165 R G G F G L G N P N R E Y E Q
Cat Felis silvestris
Mouse Mus musculus Q61496 702 76452 G154 D Q G T Q R G G G L F G S R K
Rat Rattus norvegicus Q64060 713 77937 G166 D Q G S Q R G G G L F G S R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513702 526 58299 E9 E P E D W D R E I S Q P H P A
Chicken Gallus gallus NP_990039 662 73309 S145 V P G I F G Q S K C F N S E E
Frog Xenopus laevis Q91372 700 78221 N154 R S E N G Q R N F D N R G D F
Zebra Danio Brachydanio rerio NP_571132 716 76986 T154 R D G G N E D T G R R G F G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09052 661 72313 R144 D G D E R R G R L D R E E R G
Honey Bee Apis mellifera NP_001035345 630 70500 N113 K N K D G D D N N D Y E D N D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001139665 766 79506 C189 T G H M S R E C P T K D S S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 W100 Y K S S G N R W V N G K H I P
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 E155 G P A N P R V E R E L F G T P
Conservation
Percent
Protein Identity: 100 41.7 98.9 92.8 N.A. 86 86.7 N.A. 58.1 52 54.2 57.3 N.A. 43.5 41.2 N.A. 44.7
Protein Similarity: 100 56.2 99.1 96.1 N.A. 91.4 91.5 N.A. 63.2 64.6 69.3 70.4 N.A. 58 55.7 N.A. 56.5
P-Site Identity: 100 6.6 100 60 N.A. 13.3 13.3 N.A. 0 13.3 26.6 13.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 20 100 80 N.A. 13.3 13.3 N.A. 6.6 26.6 40 20 N.A. 26.6 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.9 41.3
Protein Similarity: N.A. N.A. N.A. N.A. 53.7 54.4
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % C
% Asp: 20 7 7 14 0 14 14 0 0 20 0 20 7 20 7 % D
% Glu: 7 0 14 7 0 7 14 14 0 14 0 27 7 14 7 % E
% Phe: 0 0 0 20 7 0 0 0 7 0 20 7 7 7 7 % F
% Gly: 7 34 47 7 40 7 40 14 20 0 7 20 14 7 14 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 14 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 7 0 0 0 0 7 0 % I
% Lys: 14 7 7 0 0 0 0 0 7 0 7 7 0 0 14 % K
% Leu: 0 0 7 0 0 20 0 0 14 14 7 0 20 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 14 7 7 0 20 7 27 20 7 0 7 0 % N
% Pro: 0 27 0 7 14 0 0 0 27 0 0 7 0 7 27 % P
% Gln: 0 14 0 0 14 7 7 0 0 0 14 0 0 0 7 % Q
% Arg: 34 0 0 0 7 34 20 14 7 7 20 7 0 20 7 % R
% Ser: 0 7 7 14 7 7 0 20 0 7 0 0 27 7 7 % S
% Thr: 7 0 0 7 0 0 0 7 0 7 0 0 0 7 0 % T
% Val: 7 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _