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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
9.39
Human Site:
S190
Identified Species:
14.76
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
S190
G
S
R
R
P
V
L
S
G
T
G
N
G
D
T
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
T169
D
D
I
P
V
E
A
T
G
S
N
C
P
P
H
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
S191
G
S
R
R
P
A
L
S
G
T
G
N
G
D
T
Dog
Lupus familis
XP_544339
725
79354
S191
G
S
R
R
P
V
L
S
G
A
G
N
G
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
G180
Y
Q
S
R
S
G
S
G
R
G
G
Y
K
G
L
Rat
Rattus norvegicus
Q64060
713
77937
A192
F
Q
S
R
S
G
N
A
R
G
A
Y
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
P35
S
S
G
G
S
G
D
P
F
N
N
A
R
S
M
Chicken
Gallus gallus
NP_990039
662
73309
G171
P
G
G
R
G
A
V
G
G
P
A
G
V
L
K
Frog
Xenopus laevis
Q91372
700
78221
N180
S
Y
G
R
G
G
F
N
N
S
D
T
G
G
R
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
G180
E
G
R
G
R
G
R
G
G
F
R
G
G
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
R170
R
G
G
E
R
G
E
R
G
D
G
G
F
A
R
Honey Bee
Apis mellifera
NP_001035345
630
70500
E139
K
K
T
F
A
A
R
E
D
N
D
E
E
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
G183
C
Y
N
C
G
E
T
G
H
M
S
R
E
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
D126
F
G
V
H
D
D
P
D
Y
H
S
S
G
I
K
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
P181
F
E
K
Y
D
D
I
P
V
E
A
S
G
D
N
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
6.6
93.3
93.3
N.A.
13.3
6.6
N.A.
6.6
13.3
13.3
20
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
20
93.3
93.3
N.A.
13.3
13.3
N.A.
6.6
20
26.6
20
N.A.
13.3
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
20
7
7
0
7
20
7
0
7
7
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
7
0
7
0
% C
% Asp:
7
7
0
0
14
14
7
7
7
7
14
0
0
27
0
% D
% Glu:
7
7
0
7
0
14
7
7
0
7
0
7
14
7
0
% E
% Phe:
20
0
0
7
0
0
7
0
7
7
0
0
7
7
0
% F
% Gly:
20
27
27
14
20
40
0
27
47
14
34
20
47
20
0
% G
% His:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
7
% H
% Ile:
0
0
7
0
0
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
7
7
7
0
0
0
0
0
0
0
0
0
14
0
14
% K
% Leu:
0
0
0
0
0
0
20
0
0
0
0
0
0
7
14
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% M
% Asn:
0
0
7
0
0
0
7
7
7
14
14
20
0
0
7
% N
% Pro:
7
0
0
7
20
0
7
14
0
7
0
0
7
7
7
% P
% Gln:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
27
47
14
0
14
7
14
0
7
7
7
0
20
% R
% Ser:
14
27
14
0
20
0
7
20
0
14
14
14
0
7
0
% S
% Thr:
0
0
7
0
0
0
7
7
0
14
0
7
0
0
20
% T
% Val:
0
0
7
0
7
14
7
0
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
14
0
7
0
0
0
0
7
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _