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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
7.27
Human Site:
S237
Identified Species:
11.43
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
S237
E
A
E
G
G
E
S
S
D
T
Q
G
P
K
V
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
R216
I
P
I
I
K
G
K
R
D
L
M
A
C
A
Q
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
S238
E
A
E
G
G
E
S
S
D
T
Q
G
P
K
V
Dog
Lupus familis
XP_544339
725
79354
G238
E
A
E
G
G
E
S
G
D
T
Q
G
P
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
D227
I
P
P
P
P
P
E
D
E
D
S
I
F
A
H
Rat
Rattus norvegicus
Q64060
713
77937
D239
I
P
P
P
P
P
E
D
E
D
S
I
F
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
E82
K
Y
D
T
I
L
V
E
V
S
G
R
D
V
P
Chicken
Gallus gallus
NP_990039
662
73309
K218
Q
S
G
I
N
F
D
K
Y
D
E
C
A
V
E
Frog
Xenopus laevis
Q91372
700
78221
P227
G
N
E
K
D
E
K
P
K
K
V
T
Y
I
P
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
E227
K
L
D
Q
E
G
S
E
N
A
G
P
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
S217
D
A
I
E
I
F
S
S
G
I
A
S
G
I
H
Honey Bee
Apis mellifera
NP_001035345
630
70500
V186
Y
D
N
I
Q
V
N
V
S
G
D
N
V
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
G262
T
R
N
E
G
E
G
G
E
A
K
P
P
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
S173
M
E
N
I
K
L
A
S
F
T
K
P
T
P
V
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
V228
Q
K
Y
S
I
P
I
V
M
G
G
R
D
L
M
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
6.6
100
93.3
N.A.
0
0
N.A.
0
0
13.3
13.3
N.A.
20
0
N.A.
20
P-Site Similarity:
100
6.6
100
93.3
N.A.
6.6
6.6
N.A.
20
20
13.3
33.3
N.A.
26.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
27
0
0
0
0
7
0
0
14
7
7
7
27
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% C
% Asp:
7
7
14
0
7
0
7
14
27
20
7
0
14
0
0
% D
% Glu:
20
7
27
14
7
34
14
14
20
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
14
0
0
7
0
0
0
14
0
0
% F
% Gly:
7
0
7
20
27
14
7
14
7
14
20
20
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
20
0
14
27
20
0
7
0
0
7
0
14
0
14
0
% I
% Lys:
14
7
0
7
14
0
14
7
7
7
14
0
7
20
0
% K
% Leu:
0
7
0
0
0
14
0
0
0
7
0
0
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
7
0
7
0
0
0
7
% M
% Asn:
0
7
20
0
7
0
7
0
7
0
0
7
0
0
0
% N
% Pro:
0
20
14
14
14
20
0
7
0
0
0
20
27
14
14
% P
% Gln:
14
0
0
7
7
0
0
0
0
0
20
0
0
0
14
% Q
% Arg:
0
7
0
0
0
0
0
7
0
0
0
14
0
0
0
% R
% Ser:
0
7
0
7
0
0
34
27
7
7
14
7
0
0
7
% S
% Thr:
7
0
0
7
0
0
0
0
0
27
0
7
7
0
0
% T
% Val:
0
0
0
0
0
7
7
14
7
0
7
0
7
20
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
0
0
0
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _