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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
16.36
Human Site:
S358
Identified Species:
25.71
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
S358
M
H
D
G
I
T
A
S
R
F
K
E
L
Q
E
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
I334
D
M
M
E
R
G
K
I
G
L
D
F
C
K
Y
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
S359
M
H
D
G
I
T
A
S
R
F
K
E
L
Q
E
Dog
Lupus familis
XP_544339
725
79354
S359
M
H
D
G
I
T
A
S
R
F
K
E
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
A345
E
P
E
C
I
I
V
A
P
T
R
E
L
I
N
Rat
Rattus norvegicus
Q64060
713
77937
A357
E
P
E
C
I
I
V
A
P
T
R
E
L
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
Y200
C
V
R
P
V
V
I
Y
G
G
T
Q
T
G
H
Chicken
Gallus gallus
NP_990039
662
73309
V336
F
L
E
A
R
K
F
V
Y
G
T
C
I
R
P
Frog
Xenopus laevis
Q91372
700
78221
Q345
N
E
G
I
T
A
S
Q
Y
L
Q
L
Q
E
P
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
S347
M
T
D
G
V
A
A
S
K
F
S
E
I
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
F335
R
E
L
A
I
Q
I
F
N
E
A
R
K
F
A
Honey Bee
Apis mellifera
NP_001035345
630
70500
T304
S
L
N
S
I
L
K
T
V
V
A
Y
G
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
S383
I
T
H
G
G
C
I
S
T
F
N
V
I
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
L291
V
D
R
G
C
D
L
L
V
A
T
P
G
R
L
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
G347
L
V
D
L
I
E
R
G
R
I
S
L
C
N
I
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
0
100
100
N.A.
20
20
N.A.
0
0
0
60
N.A.
6.6
6.6
N.A.
33.3
P-Site Similarity:
100
6.6
100
100
N.A.
40
40
N.A.
13.3
20
20
80
N.A.
6.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
14
27
14
0
7
14
0
0
0
7
% A
% Cys:
7
0
0
14
7
7
0
0
0
0
0
7
14
0
0
% C
% Asp:
7
7
34
0
0
7
0
0
0
0
7
0
0
0
0
% D
% Glu:
14
14
20
7
0
7
0
0
0
7
0
40
0
7
34
% E
% Phe:
7
0
0
0
0
0
7
7
0
34
0
7
0
7
0
% F
% Gly:
0
0
7
40
7
7
0
7
14
14
0
0
14
14
0
% G
% His:
0
20
7
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
7
54
14
20
7
0
7
0
0
20
14
7
% I
% Lys:
0
0
0
0
0
7
14
0
7
0
20
0
7
7
0
% K
% Leu:
7
14
7
7
0
7
7
7
0
14
0
14
34
0
7
% L
% Met:
27
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
0
7
0
7
0
0
7
14
% N
% Pro:
0
14
0
7
0
0
0
0
14
0
0
7
0
0
14
% P
% Gln:
0
0
0
0
0
7
0
7
0
0
7
7
7
34
0
% Q
% Arg:
7
0
14
0
14
0
7
0
27
0
14
7
0
14
0
% R
% Ser:
7
0
0
7
0
0
7
34
0
0
14
0
0
0
0
% S
% Thr:
0
14
0
0
7
20
0
7
7
14
20
0
7
0
7
% T
% Val:
7
14
0
0
14
7
14
7
14
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
14
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _