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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
23.94
Human Site:
S465
Identified Species:
37.62
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
S465
P
E
M
K
K
L
I
S
C
P
G
M
P
S
K
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S427
V
E
D
L
D
K
R
S
F
L
L
D
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
S466
P
E
M
K
K
L
I
S
C
P
G
M
P
S
K
Dog
Lupus familis
XP_544339
725
79354
S466
P
E
M
K
K
L
I
S
C
P
G
M
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
S438
P
E
M
K
K
L
I
S
C
P
G
M
P
S
K
Rat
Rattus norvegicus
Q64060
713
77937
S450
P
E
M
K
K
L
I
S
C
P
G
M
P
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
G293
E
E
I
Q
R
L
A
G
E
F
L
K
T
E
Y
Chicken
Gallus gallus
NP_990039
662
73309
A429
R
Q
T
L
M
F
S
A
T
F
P
E
E
V
Q
Frog
Xenopus laevis
Q91372
700
78221
T451
P
E
I
E
K
L
M
T
K
P
G
M
P
T
K
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
A454
P
E
M
R
K
L
V
A
S
P
G
M
P
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
T428
T
M
R
P
E
H
Q
T
L
M
F
S
A
T
F
Honey Bee
Apis mellifera
NP_001035345
630
70500
Q397
A
T
F
P
D
E
V
Q
H
L
A
R
R
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
E490
P
D
I
Q
R
L
I
E
H
P
H
M
P
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
E384
G
R
V
G
S
T
S
E
N
I
T
Q
R
I
L
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
L444
D
I
D
K
R
S
V
L
L
D
I
L
H
T
H
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
0
60
73.3
N.A.
0
0
N.A.
46.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
33.3
20
93.3
93.3
N.A.
20
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
14
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% C
% Asp:
7
7
14
0
14
0
0
0
0
7
0
7
0
0
0
% D
% Glu:
7
60
0
7
7
7
0
14
7
0
0
7
7
7
0
% E
% Phe:
0
0
7
0
0
7
0
0
7
14
7
0
0
7
7
% F
% Gly:
7
0
0
7
0
0
0
7
0
0
47
0
0
0
7
% G
% His:
0
0
0
0
0
7
0
0
14
0
7
0
7
0
7
% H
% Ile:
0
7
20
0
0
0
40
0
0
7
7
0
7
7
0
% I
% Lys:
0
0
0
40
47
7
0
0
7
0
0
7
0
0
54
% K
% Leu:
0
0
0
14
0
60
0
7
14
14
14
7
0
7
14
% L
% Met:
0
7
40
0
7
0
7
0
0
7
0
54
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
54
0
0
14
0
0
0
0
0
54
7
0
54
0
0
% P
% Gln:
0
7
0
14
0
0
7
7
0
0
0
7
0
0
7
% Q
% Arg:
7
7
7
7
20
0
7
0
0
0
0
7
14
0
0
% R
% Ser:
0
0
0
0
7
7
14
40
7
0
0
7
0
40
0
% S
% Thr:
7
7
7
0
0
7
0
14
7
0
7
0
7
20
0
% T
% Val:
7
0
7
0
0
0
20
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _