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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
10.3
Human Site:
T220
Identified Species:
16.19
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
T220
G
L
N
E
E
V
I
T
G
S
G
K
N
S
W
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
T199
N
I
Q
L
T
R
Y
T
R
P
T
P
V
Q
K
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
T221
G
L
N
E
E
V
I
T
G
S
G
K
N
S
W
Dog
Lupus familis
XP_544339
725
79354
T221
G
L
N
E
E
V
I
T
S
S
G
K
N
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
S210
E
T
E
G
G
E
S
S
D
S
Q
G
P
K
V
Rat
Rattus norvegicus
Q64060
713
77937
S222
E
A
E
G
G
E
S
S
D
I
Q
G
P
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
A65
E
D
E
A
S
I
F
A
H
Y
Q
T
G
I
N
Chicken
Gallus gallus
NP_990039
662
73309
E201
Y
V
P
P
P
P
P
E
D
E
Q
S
I
F
A
Frog
Xenopus laevis
Q91372
700
78221
G210
K
G
R
N
E
E
V
G
V
E
S
G
K
S
Q
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
E210
G
F
R
G
R
N
E
E
V
F
S
K
V
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
E200
E
D
V
E
R
K
R
E
F
Y
I
P
P
E
P
Honey Bee
Apis mellifera
NP_001035345
630
70500
G169
E
K
S
L
F
E
N
G
V
E
I
G
I
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
H245
F
R
C
Q
E
E
G
H
F
A
K
E
C
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
F156
V
P
E
P
I
L
D
F
S
S
P
P
L
D
E
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
L211
H
L
I
S
N
I
Q
L
A
R
Y
N
V
P
T
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
6.6
100
93.3
N.A.
6.6
0
N.A.
0
0
13.3
13.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
13.3
6.6
N.A.
6.6
6.6
20
20
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
7
7
7
0
0
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
14
0
0
0
0
7
0
20
0
0
0
0
7
0
% D
% Glu:
34
0
27
27
34
34
7
20
0
20
0
7
0
7
7
% E
% Phe:
7
7
0
0
7
0
7
7
14
7
0
0
0
7
7
% F
% Gly:
27
7
0
20
14
0
7
14
14
0
20
27
7
0
0
% G
% His:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
7
14
20
0
0
7
14
0
14
7
0
% I
% Lys:
7
7
0
0
0
7
0
0
0
0
7
27
7
14
7
% K
% Leu:
0
27
0
14
0
7
0
7
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
20
7
7
7
7
0
0
0
0
7
20
7
14
% N
% Pro:
0
7
7
14
7
7
7
0
0
7
7
20
20
14
7
% P
% Gln:
0
0
7
7
0
0
7
0
0
0
27
0
0
7
7
% Q
% Arg:
0
7
14
0
14
7
7
0
7
7
0
0
0
0
0
% R
% Ser:
0
0
7
7
7
0
14
14
14
34
14
7
0
27
0
% S
% Thr:
0
7
0
0
7
0
0
27
0
0
7
7
0
7
14
% T
% Val:
7
7
7
0
0
20
7
0
20
0
0
0
20
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% W
% Tyr:
7
0
0
0
0
0
7
0
0
14
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _