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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
9.09
Human Site:
T356
Identified Species:
14.29
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
T356
H
M
M
H
D
G
I
T
A
S
R
F
K
E
L
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
G332
L
V
D
M
M
E
R
G
K
I
G
L
D
F
C
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
T357
H
M
M
H
D
G
I
T
A
S
R
F
K
E
L
Dog
Lupus familis
XP_544339
725
79354
T357
H
M
M
H
D
G
I
T
A
S
R
F
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
I343
L
Q
E
P
E
C
I
I
V
A
P
T
R
E
L
Rat
Rattus norvegicus
Q64060
713
77937
I355
L
Q
E
P
E
C
I
I
V
A
P
T
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
V198
G
T
C
V
R
P
V
V
I
Y
G
G
T
Q
T
Chicken
Gallus gallus
NP_990039
662
73309
K334
Q
I
F
L
E
A
R
K
F
V
Y
G
T
C
I
Frog
Xenopus laevis
Q91372
700
78221
A343
M
M
N
E
G
I
T
A
S
Q
Y
L
Q
L
Q
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
A345
R
F
M
T
D
G
V
A
A
S
K
F
S
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
Q333
P
T
R
E
L
A
I
Q
I
F
N
E
A
R
K
Honey Bee
Apis mellifera
NP_001035345
630
70500
L302
K
F
S
L
N
S
I
L
K
T
V
V
A
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
C381
N
M
I
T
H
G
G
C
I
S
T
F
N
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
D289
R
E
V
D
R
G
C
D
L
L
V
A
T
P
G
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
E345
G
R
L
V
D
L
I
E
R
G
R
I
S
L
C
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
0
100
100
N.A.
20
20
N.A.
0
0
6.6
46.6
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
6.6
100
100
N.A.
40
40
N.A.
13.3
20
20
66.6
N.A.
6.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
0
14
27
14
0
7
14
0
0
% A
% Cys:
0
0
7
0
0
14
7
7
0
0
0
0
0
7
14
% C
% Asp:
0
0
7
7
34
0
0
7
0
0
0
0
7
0
0
% D
% Glu:
0
7
14
14
20
7
0
7
0
0
0
7
0
40
0
% E
% Phe:
0
14
7
0
0
0
0
0
7
7
0
34
0
7
0
% F
% Gly:
14
0
0
0
7
40
7
7
0
7
14
14
0
0
14
% G
% His:
20
0
0
20
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
7
54
14
20
7
0
7
0
0
20
% I
% Lys:
7
0
0
0
0
0
0
7
14
0
7
0
20
0
7
% K
% Leu:
20
0
7
14
7
7
0
7
7
7
0
14
0
14
34
% L
% Met:
7
34
27
7
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
7
0
0
14
0
7
0
0
0
0
14
0
0
7
0
% P
% Gln:
7
14
0
0
0
0
0
7
0
7
0
0
7
7
7
% Q
% Arg:
14
7
7
0
14
0
14
0
7
0
27
0
14
7
0
% R
% Ser:
0
0
7
0
0
7
0
0
7
34
0
0
14
0
0
% S
% Thr:
0
14
0
14
0
0
7
20
0
7
7
14
20
0
7
% T
% Val:
0
7
7
14
0
0
14
7
14
7
14
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
14
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _