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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
33.03
Human Site:
T477
Identified Species:
51.9
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
T477
P
S
K
E
Q
R
Q
T
L
M
F
S
A
T
F
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
D439
I
L
G
A
A
G
T
D
S
L
T
L
V
F
V
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
T478
P
S
K
E
Q
R
Q
T
L
M
F
S
A
T
F
Dog
Lupus familis
XP_544339
725
79354
T478
P
S
K
E
Q
R
Q
T
L
M
F
S
A
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
T450
P
S
K
E
Q
R
Q
T
L
L
F
S
A
T
F
Rat
Rattus norvegicus
Q64060
713
77937
T462
P
S
K
E
Q
R
Q
T
L
L
F
S
A
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
V305
T
E
Y
L
F
V
A
V
G
Q
V
G
G
A
C
Chicken
Gallus gallus
NP_990039
662
73309
E441
E
V
Q
R
L
A
G
E
F
L
K
T
D
Y
I
Frog
Xenopus laevis
Q91372
700
78221
T463
P
T
K
E
K
R
Q
T
L
M
F
S
A
T
Y
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
T466
P
S
K
E
E
R
Q
T
L
M
F
S
A
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
Q440
A
T
F
P
E
E
I
Q
R
M
A
G
E
F
L
Honey Bee
Apis mellifera
NP_001035345
630
70500
F409
R
F
L
N
N
Y
L
F
L
A
V
G
I
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
T502
P
A
K
G
D
R
Q
T
L
M
F
S
A
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
M396
R
I
L
Y
V
D
D
M
D
K
K
S
A
L
L
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
T456
H
T
H
A
G
G
L
T
L
I
F
V
E
T
K
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
0
80
86.6
N.A.
6.6
6.6
N.A.
80
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
0
20
100
100
N.A.
20
6.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
14
7
7
7
0
0
7
7
0
60
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
7
7
7
7
0
0
0
7
0
0
% D
% Glu:
7
7
0
47
14
7
0
7
0
0
0
0
14
0
0
% E
% Phe:
0
7
7
0
7
0
0
7
7
0
60
0
0
14
40
% F
% Gly:
0
0
7
7
7
14
7
0
7
0
0
20
7
0
7
% G
% His:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
7
0
0
7
0
0
7
0
7
% I
% Lys:
0
0
54
0
7
0
0
0
0
7
14
0
0
0
7
% K
% Leu:
0
7
14
7
7
0
14
0
67
27
0
7
0
7
14
% L
% Met:
0
0
0
0
0
0
0
7
0
47
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
54
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
34
0
54
7
0
7
0
0
0
0
0
% Q
% Arg:
14
0
0
7
0
54
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
40
0
0
0
0
0
0
7
0
0
60
0
0
0
% S
% Thr:
7
20
0
0
0
0
7
60
0
0
7
7
0
60
0
% T
% Val:
0
7
0
0
7
7
0
7
0
0
14
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
7
0
0
0
0
0
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _