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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX4
All Species:
19.09
Human Site:
Y400
Identified Species:
30
UniProt:
Q9NQI0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQI0
NP_001129506.1
724
79308
Y400
C
V
R
A
V
V
I
Y
G
G
T
Q
L
G
H
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
H375
M
P
P
K
G
V
R
H
T
M
M
F
S
A
T
Rhesus Macaque
Macaca mulatta
XP_001100045
725
79200
Y401
C
V
R
A
V
V
I
Y
G
G
T
Q
L
G
H
Dog
Lupus familis
XP_544339
725
79354
Y401
C
V
R
A
V
V
I
Y
G
G
T
Q
L
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61496
702
76452
V386
G
H
S
V
R
Q
I
V
Q
G
C
N
I
L
C
Rat
Rattus norvegicus
Q64060
713
77937
V398
G
H
S
I
R
Q
I
V
Q
G
C
N
I
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513702
526
58299
K241
K
I
G
L
S
H
I
K
Y
L
V
L
D
E
A
Chicken
Gallus gallus
NP_990039
662
73309
I377
P
G
R
L
L
D
I
I
E
K
G
K
I
S
L
Frog
Xenopus laevis
Q91372
700
78221
Y386
C
V
R
P
V
V
V
Y
G
G
I
Q
P
V
H
Zebra Danio
Brachydanio rerio
NP_571132
716
76986
Y389
C
V
R
P
V
V
V
Y
G
G
I
N
T
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
P376
C
H
V
V
I
A
T
P
G
R
L
L
D
F
V
Honey Bee
Apis mellifera
NP_001035345
630
70500
F345
V
E
K
G
R
V
K
F
S
S
V
Q
F
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001139665
766
79506
Y425
T
I
R
P
V
V
V
Y
G
G
T
S
V
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
I332
D
M
G
F
E
P
Q
I
R
H
I
V
E
E
C
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
R389
D
M
P
K
V
N
D
R
Q
T
L
M
F
S
A
Conservation
Percent
Protein Identity:
100
41.7
98.9
92.8
N.A.
86
86.7
N.A.
58.1
52
54.2
57.3
N.A.
43.5
41.2
N.A.
44.7
Protein Similarity:
100
56.2
99.1
96.1
N.A.
91.4
91.5
N.A.
63.2
64.6
69.3
70.4
N.A.
58
55.7
N.A.
56.5
P-Site Identity:
100
6.6
100
93.3
N.A.
13.3
13.3
N.A.
6.6
13.3
66.6
60
N.A.
13.3
13.3
N.A.
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
20
20
N.A.
13.3
33.3
73.3
73.3
N.A.
20
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.9
41.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.7
54.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
7
0
0
0
0
0
0
0
7
14
% A
% Cys:
40
0
0
0
0
0
0
0
0
0
14
0
0
0
20
% C
% Asp:
14
0
0
0
0
7
7
0
0
0
0
0
14
0
0
% D
% Glu:
0
7
0
0
7
0
0
0
7
0
0
0
7
14
0
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
0
7
14
7
0
% F
% Gly:
14
7
14
7
7
0
0
0
47
54
7
0
0
27
0
% G
% His:
0
20
0
0
0
7
0
7
0
7
0
0
0
0
27
% H
% Ile:
0
14
0
7
7
0
47
14
0
0
20
0
20
0
0
% I
% Lys:
7
0
7
14
0
0
7
7
0
7
0
7
0
0
0
% K
% Leu:
0
0
0
14
7
0
0
0
0
7
14
14
20
20
7
% L
% Met:
7
14
0
0
0
0
0
0
0
7
7
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
20
0
0
0
% N
% Pro:
7
7
14
20
0
7
0
7
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
14
7
0
20
0
0
34
0
0
0
% Q
% Arg:
0
0
47
0
20
0
7
7
7
7
0
0
0
0
0
% R
% Ser:
0
0
14
0
7
0
0
0
7
7
0
7
7
20
0
% S
% Thr:
7
0
0
0
0
0
7
0
7
7
27
0
7
0
7
% T
% Val:
7
34
7
14
47
54
20
14
0
0
14
7
7
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
7
0
0
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _