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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFDN4
All Species:
23.94
Human Site:
S125
Identified Species:
40.51
UniProt:
Q9NQP4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQP4
NP_002614.2
134
15314
S125
Q
L
Y
A
K
F
G
S
N
I
N
L
E
A
D
Chimpanzee
Pan troglodytes
XP_528018
111
12604
L101
L
Q
E
A
T
D
A
L
E
S
K
V
E
A
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534459
133
15200
S124
Q
L
Y
A
K
F
G
S
N
I
N
L
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_001103622
134
15220
S125
Q
L
Y
A
K
F
G
S
N
I
N
L
E
A
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509242
134
15242
S125
Q
L
Y
A
K
F
G
S
N
I
N
L
E
A
D
Chicken
Gallus gallus
XP_417503
134
15382
N125
Q
L
Y
A
K
F
G
N
N
I
N
L
E
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_701018
88
9987
T80
I
S
H
S
Q
E
E
T
Q
E
M
L
E
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRL3
138
15917
S130
H
L
Y
Q
R
F
G
S
N
I
S
L
E
A
E
Honey Bee
Apis mellifera
XP_001120811
137
16054
S128
K
L
Y
A
K
F
G
S
R
I
N
L
E
A
E
Nematode Worm
Caenorhab. elegans
Q17435
126
14013
D118
V
L
Y
A
K
F
G
D
Q
I
N
L
D
A
E
Sea Urchin
Strong. purpuratus
XP_788846
137
15077
K128
Q
L
Y
A
K
F
G
K
N
I
N
L
E
M
D
Poplar Tree
Populus trichocarpa
XP_002328490
126
14522
F117
K
K
I
L
Y
G
K
F
G
E
S
I
N
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M4B5
128
14719
K118
L
K
K
V
L
Y
A
K
F
K
D
S
I
N
L
Baker's Yeast
Sacchar. cerevisiae
P53900
129
15162
I116
R
L
D
A
L
K
A
I
L
Y
A
K
F
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
N.A.
91.7
N.A.
97
N.A.
N.A.
93.2
91.7
N.A.
54.4
N.A.
42
50.3
33.5
56.2
Protein Similarity:
100
73.1
N.A.
95.5
N.A.
97.7
N.A.
N.A.
97.7
97.7
N.A.
61.1
N.A.
72.4
70.8
53.7
72.9
P-Site Identity:
100
20
N.A.
100
N.A.
100
N.A.
N.A.
100
86.6
N.A.
20
N.A.
66.6
80
66.6
86.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
N.A.
46.6
N.A.
86.6
93.3
80
86.6
Percent
Protein Identity:
35
N.A.
N.A.
38
35
N.A.
Protein Similarity:
60.4
N.A.
N.A.
64.9
55.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
72
0
0
22
0
0
0
8
0
0
72
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
8
0
0
8
0
8
0
43
% D
% Glu:
0
0
8
0
0
8
8
0
8
15
0
0
72
0
36
% E
% Phe:
0
0
0
0
0
65
0
8
8
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
65
0
8
0
0
0
0
8
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
65
0
8
8
0
8
% I
% Lys:
15
15
8
0
58
8
8
15
0
8
8
8
0
0
0
% K
% Leu:
15
72
0
8
15
0
0
8
8
0
0
72
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
50
0
58
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
43
8
0
8
8
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
43
0
8
15
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
0
8
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _