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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD8
All Species:
17.27
Human Site:
S185
Identified Species:
31.67
UniProt:
Q9NQR1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQR1
NP_065115.3
393
42890
S185
P
P
K
T
P
P
S
S
C
D
S
T
N
A
A
Chimpanzee
Pan troglodytes
XP_509461
536
57357
S328
P
P
K
T
P
P
S
S
C
D
S
T
N
A
A
Rhesus Macaque
Macaca mulatta
XP_001097869
395
44029
S187
P
P
K
T
P
P
S
S
C
D
S
T
N
A
A
Dog
Lupus familis
XP_853243
445
49139
S237
P
P
K
T
P
T
S
S
C
D
P
P
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q2YDW7
349
38827
S142
P
P
K
T
P
P
P
S
C
D
S
T
N
V
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507341
326
37086
P134
A
K
Q
A
L
K
K
P
V
K
A
N
Q
A
S
Chicken
Gallus gallus
XP_415116
326
36584
M135
A
K
P
A
Q
K
K
M
V
K
A
K
R
G
P
Frog
Xenopus laevis
Q498E6
336
38273
P136
Q
R
N
T
A
L
T
P
V
D
K
L
Q
S
Q
Zebra Danio
Brachydanio rerio
Q071E0
344
39137
I142
C
I
H
S
A
A
D
I
T
S
S
K
H
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFK6
691
76475
A239
D
F
Q
T
H
R
S
A
L
R
D
S
H
S
S
Honey Bee
Apis mellifera
XP_395493
367
42247
R171
K
P
P
N
R
G
R
R
K
L
N
N
N
H
S
Nematode Worm
Caenorhab. elegans
Q22795
242
27550
R55
P
S
K
N
T
R
S
R
K
G
V
S
V
K
D
Sea Urchin
Strong. purpuratus
XP_797080
405
43943
S194
G
Q
L
E
V
E
A
S
P
K
N
T
G
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
82.7
71.9
N.A.
80.9
N.A.
N.A.
61.5
61
51.4
44
N.A.
26.9
27.7
29
33.8
Protein Similarity:
100
71.4
83.5
75.2
N.A.
84.7
N.A.
N.A.
68.4
68.9
63.3
58.5
N.A.
37.7
46.8
41.2
52.1
P-Site Identity:
100
100
100
66.6
N.A.
86.6
N.A.
N.A.
6.6
0
13.3
6.6
N.A.
13.3
13.3
20
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
86.6
N.A.
N.A.
26.6
6.6
26.6
20
N.A.
53.3
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
16
8
8
8
0
0
16
0
0
31
39
% A
% Cys:
8
0
0
0
0
0
0
0
39
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
47
8
0
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
8
0
0
8
8
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
16
8
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
8
16
47
0
0
16
16
0
16
24
8
16
0
8
8
% K
% Leu:
0
0
8
0
8
8
0
0
8
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
16
0
0
0
0
0
0
16
16
39
0
0
% N
% Pro:
47
47
16
0
39
31
8
16
8
0
8
8
0
0
8
% P
% Gln:
8
8
16
0
8
0
0
0
0
0
0
0
16
0
8
% Q
% Arg:
0
8
0
0
8
16
8
16
0
8
0
0
8
16
0
% R
% Ser:
0
8
0
8
0
0
47
47
0
8
39
16
0
16
24
% S
% Thr:
0
0
0
54
8
8
8
0
8
0
0
39
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
24
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _