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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD8
All Species:
17.58
Human Site:
T189
Identified Species:
32.22
UniProt:
Q9NQR1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQR1
NP_065115.3
393
42890
T189
P
P
S
S
C
D
S
T
N
A
A
I
A
K
Q
Chimpanzee
Pan troglodytes
XP_509461
536
57357
T332
P
P
S
S
C
D
S
T
N
A
A
I
A
K
Q
Rhesus Macaque
Macaca mulatta
XP_001097869
395
44029
T191
P
P
S
S
C
D
S
T
N
A
A
I
T
K
Q
Dog
Lupus familis
XP_853243
445
49139
P241
P
T
S
S
C
D
P
P
I
T
A
I
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q2YDW7
349
38827
T146
P
P
P
S
C
D
S
T
N
V
A
V
A
K
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507341
326
37086
N138
L
K
K
P
V
K
A
N
Q
A
S
R
R
K
V
Chicken
Gallus gallus
XP_415116
326
36584
K139
Q
K
K
M
V
K
A
K
R
G
P
R
R
K
T
Frog
Xenopus laevis
Q498E6
336
38273
L140
A
L
T
P
V
D
K
L
Q
S
Q
K
M
V
K
Zebra Danio
Brachydanio rerio
Q071E0
344
39137
K146
A
A
D
I
T
S
S
K
H
R
K
P
A
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFK6
691
76475
S243
H
R
S
A
L
R
D
S
H
S
S
T
H
S
S
Honey Bee
Apis mellifera
XP_395493
367
42247
N175
R
G
R
R
K
L
N
N
N
H
S
S
A
I
Y
Nematode Worm
Caenorhab. elegans
Q22795
242
27550
S59
T
R
S
R
K
G
V
S
V
K
D
V
S
N
H
Sea Urchin
Strong. purpuratus
XP_797080
405
43943
T198
V
E
A
S
P
K
N
T
G
R
G
R
G
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
82.7
71.9
N.A.
80.9
N.A.
N.A.
61.5
61
51.4
44
N.A.
26.9
27.7
29
33.8
Protein Similarity:
100
71.4
83.5
75.2
N.A.
84.7
N.A.
N.A.
68.4
68.9
63.3
58.5
N.A.
37.7
46.8
41.2
52.1
P-Site Identity:
100
100
93.3
66.6
N.A.
80
N.A.
N.A.
13.3
6.6
6.6
13.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
100
93.3
66.6
N.A.
86.6
N.A.
N.A.
26.6
13.3
26.6
33.3
N.A.
40
26.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
0
0
16
0
0
31
39
0
47
0
0
% A
% Cys:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
47
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
8
8
8
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
16
8
0
0
8
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
31
0
8
0
% I
% Lys:
0
16
16
0
16
24
8
16
0
8
8
8
0
54
16
% K
% Leu:
8
8
0
0
8
8
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
16
16
39
0
0
0
0
8
0
% N
% Pro:
39
31
8
16
8
0
8
8
0
0
8
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
16
0
8
0
0
0
39
% Q
% Arg:
8
16
8
16
0
8
0
0
8
16
0
24
16
16
8
% R
% Ser:
0
0
47
47
0
8
39
16
0
16
24
8
8
8
8
% S
% Thr:
8
8
8
0
8
0
0
39
0
8
0
8
8
0
8
% T
% Val:
8
0
0
0
24
0
8
0
8
8
0
16
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _