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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD8
All Species:
22.42
Human Site:
Y96
Identified Species:
41.11
UniProt:
Q9NQR1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQR1
NP_065115.3
393
42890
Y96
F
T
G
Q
S
K
I
Y
S
Y
M
S
P
N
K
Chimpanzee
Pan troglodytes
XP_509461
536
57357
Y239
F
T
G
Q
S
K
I
Y
S
Y
M
S
P
N
K
Rhesus Macaque
Macaca mulatta
XP_001097869
395
44029
Y98
F
T
G
Q
S
K
I
Y
S
Y
M
S
P
N
K
Dog
Lupus familis
XP_853243
445
49139
Y148
F
T
G
Q
S
K
I
Y
S
Y
M
S
P
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q2YDW7
349
38827
Y53
F
A
G
Q
S
K
I
Y
A
Y
M
S
P
N
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507341
326
37086
T51
L
Q
E
E
N
S
V
T
H
H
E
I
K
C
P
Chicken
Gallus gallus
XP_415116
326
36584
V51
P
L
Q
E
E
N
S
V
M
Y
H
E
V
K
C
Frog
Xenopus laevis
Q498E6
336
38273
S51
P
K
I
Y
S
Y
M
S
P
T
K
S
P
S
G
Zebra Danio
Brachydanio rerio
Q071E0
344
39137
A59
N
R
T
A
R
P
E
A
T
M
S
G
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFK6
691
76475
K113
A
A
A
K
D
S
Q
K
T
I
H
T
E
E
Q
Honey Bee
Apis mellifera
XP_395493
367
42247
Y68
V
C
I
S
S
F
F
Y
T
Q
V
Y
I
S
K
Nematode Worm
Caenorhab. elegans
Q22795
242
27550
Sea Urchin
Strong. purpuratus
XP_797080
405
43943
V101
P
S
P
D
A
T
L
V
Y
P
L
D
P
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
82.7
71.9
N.A.
80.9
N.A.
N.A.
61.5
61
51.4
44
N.A.
26.9
27.7
29
33.8
Protein Similarity:
100
71.4
83.5
75.2
N.A.
84.7
N.A.
N.A.
68.4
68.9
63.3
58.5
N.A.
37.7
46.8
41.2
52.1
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
0
6.6
20
0
N.A.
0
20
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
26.6
13.3
33.3
6.6
N.A.
26.6
40
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
8
8
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
8
8
8
0
% D
% Glu:
0
0
8
16
8
0
8
0
0
0
8
8
8
8
0
% E
% Phe:
39
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
39
0
0
0
0
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
16
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
39
0
0
8
0
8
8
0
0
% I
% Lys:
0
8
0
8
0
39
0
8
0
0
8
0
8
8
47
% K
% Leu:
8
8
0
0
0
0
8
0
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
8
8
39
0
0
0
0
% M
% Asn:
8
0
0
0
8
8
0
0
0
0
0
0
0
39
0
% N
% Pro:
24
0
8
0
0
8
0
0
8
8
0
0
54
0
8
% P
% Gln:
0
8
8
39
0
0
8
0
0
8
0
0
0
0
8
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
54
16
8
8
31
0
8
47
0
16
8
% S
% Thr:
0
31
8
0
0
8
0
8
24
8
0
8
0
0
0
% T
% Val:
8
0
0
0
0
0
8
16
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
47
8
47
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _