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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT2 All Species: 19.7
Human Site: S266 Identified Species: 30.95
UniProt: Q9NQR4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQR4 NP_064587.1 276 30608 S266 P V F R Q K R S D L Y A V E M
Chimpanzee Pan troglodytes XP_526254 411 44922 S401 P V F R Q K R S D L Y A V E M
Rhesus Macaque Macaca mulatta XP_001091514 326 35729 S316 P V F R Q K R S D L Y A V E M
Dog Lupus familis XP_535718 323 35097 S313 P I F S Q K R S D L Y A V E A
Cat Felis silvestris
Mouse Mus musculus Q9JHW2 276 30483 A266 P I L K Q K R A D L Y T V E S
Rat Rattus norvegicus Q497B0 276 30682 A266 P I L K Q K R A D L Y S V E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416604 275 30350 Y266 P I L S Q K R Y D L Y G I E M
Frog Xenopus laevis Q6INI7 276 30746 D266 P I R R Q R R D N L Y T V E E
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 N266 P I T K Q R R N D L Y S V N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 N297 P C F E H R R N D I Y A L T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76463 440 49917 S282 P V F S H R R S D L Y T L H I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309478 370 40453 G355 P L T K Q R R G D L Y Q L V D
Maize Zea mays NP_001146295 362 38604 G348 P V Q H Q R R G D L Y Q L V D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 P313 G V F R D R R P D L Y K V L L
Baker's Yeast Sacchar. cerevisiae P49954 291 32531 F282 P L T K Q R R F D V Y S D V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.6 83.7 76.1 N.A. 89.4 88.4 N.A. N.A. 81.1 78.9 74.3 N.A. 23.7 N.A. 26.3 N.A.
Protein Similarity: 100 66.6 84.3 81.4 N.A. 95.6 95.2 N.A. N.A. 91.3 90.5 89.8 N.A. 37.8 N.A. 39.5 N.A.
P-Site Identity: 100 100 100 80 N.A. 60 60 N.A. N.A. 60 53.3 46.6 N.A. 40 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 80 86.6 N.A. N.A. 73.3 73.3 80 N.A. 66.6 N.A. 73.3 N.A.
Percent
Protein Identity: 44.8 44.2 N.A. 23.6 46.7 N.A.
Protein Similarity: 55.6 55.5 N.A. 39.2 67 N.A.
P-Site Identity: 40 46.6 N.A. 53.3 33.3 N.A.
P-Site Similarity: 66.6 60 N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 14 0 0 0 34 0 0 14 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 7 94 0 0 0 7 0 14 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 0 0 54 7 % E
% Phe: 0 0 47 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 14 0 0 0 7 0 0 0 % G
% His: 0 0 0 7 14 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 40 0 0 0 0 0 0 0 7 0 0 7 0 7 % I
% Lys: 0 0 0 34 0 47 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 14 20 0 0 0 0 0 0 87 0 0 27 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27 % M
% Asn: 0 0 0 0 0 0 0 14 7 0 0 0 0 7 7 % N
% Pro: 94 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 80 0 0 0 0 0 0 14 0 0 0 % Q
% Arg: 0 0 7 34 0 54 100 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 20 0 0 0 34 0 0 0 20 0 0 20 % S
% Thr: 0 0 20 0 0 0 0 0 0 0 0 20 0 7 0 % T
% Val: 0 40 0 0 0 0 0 0 0 7 0 0 60 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 100 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _