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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT2 All Species: 33.94
Human Site: S70 Identified Species: 53.33
UniProt: Q9NQR4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQR4 NP_064587.1 276 30608 S70 G E S T Q K L S E V A K E C S
Chimpanzee Pan troglodytes XP_526254 411 44922 C205 G E S T Q K L C E V A K E C S
Rhesus Macaque Macaca mulatta XP_001091514 326 35729 S120 G E S T Q K L S E V A K E C S
Dog Lupus familis XP_535718 323 35097 S117 G E S T Q K L S E V A K E C S
Cat Felis silvestris
Mouse Mus musculus Q9JHW2 276 30483 S70 G E S T Q K L S E V A K E S S
Rat Rattus norvegicus Q497B0 276 30682 S70 G E S T K K L S E V A K E N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416604 275 30350 S70 G E S T Q K L S A V A K E C S
Frog Xenopus laevis Q6INI7 276 30746 S70 G E S T E L L S Q V A K E C G
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 S70 G E S T Q V L S E T A K K C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 R100 G E L M A Q Y R E L A K C N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76463 440 49917 R86 E K Y R E L A R K H N I W L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309478 370 40453 S159 S P S T A M L S E A A G L L K
Maize Zea mays NP_001146295 362 38604 S152 A P S F S M L S E V A R S L Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 T103 K P Y K N H P T I A R M Q K L
Baker's Yeast Sacchar. cerevisiae P49954 291 32531 L86 S V Q F L S N L A N K F K I I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.6 83.7 76.1 N.A. 89.4 88.4 N.A. N.A. 81.1 78.9 74.3 N.A. 23.7 N.A. 26.3 N.A.
Protein Similarity: 100 66.6 84.3 81.4 N.A. 95.6 95.2 N.A. N.A. 91.3 90.5 89.8 N.A. 37.8 N.A. 39.5 N.A.
P-Site Identity: 100 93.3 100 100 N.A. 93.3 86.6 N.A. N.A. 93.3 73.3 73.3 N.A. 33.3 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 86.6 80 N.A. 46.6 N.A. 26.6 N.A.
Percent
Protein Identity: 44.8 44.2 N.A. 23.6 46.7 N.A.
Protein Similarity: 55.6 55.5 N.A. 39.2 67 N.A.
P-Site Identity: 40 40 N.A. 0 0 N.A.
P-Site Similarity: 40 46.6 N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 14 0 7 0 14 14 80 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 7 47 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 67 0 0 14 0 0 0 67 0 0 0 54 0 0 % E
% Phe: 0 0 0 14 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 67 0 0 0 0 0 0 0 0 0 0 7 0 0 14 % G
% His: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 7 0 7 7 % I
% Lys: 7 7 0 7 7 47 0 0 7 0 7 67 14 7 14 % K
% Leu: 0 0 7 0 7 14 74 7 0 7 0 0 7 20 7 % L
% Met: 0 0 0 7 0 14 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 7 0 7 0 0 7 7 0 0 14 0 % N
% Pro: 0 20 0 0 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 47 7 0 0 7 0 0 0 7 0 7 % Q
% Arg: 0 0 0 7 0 0 0 14 0 0 7 7 0 0 0 % R
% Ser: 14 0 74 0 7 7 0 67 0 0 0 0 7 7 54 % S
% Thr: 0 0 0 67 0 0 0 7 0 7 0 0 0 0 0 % T
% Val: 0 7 0 0 0 7 0 0 0 60 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 14 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _