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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NIT2
All Species:
46.97
Human Site:
Y216
Identified Species:
73.81
UniProt:
Q9NQR4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQR4
NP_064587.1
276
30608
Y216
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
T
Chimpanzee
Pan troglodytes
XP_526254
411
44922
Y351
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
T
Rhesus Macaque
Macaca mulatta
XP_001091514
326
35729
Y266
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
T
Dog
Lupus familis
XP_535718
323
35097
Y263
A
R
D
E
Q
A
S
Y
V
A
W
G
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHW2
276
30483
Y216
A
R
D
D
K
A
S
Y
V
A
W
G
H
S
T
Rat
Rattus norvegicus
Q497B0
276
30682
Y216
A
R
D
E
K
A
S
Y
V
A
W
G
H
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416604
275
30350
Y216
A
R
D
E
K
A
S
Y
V
A
W
G
H
S
T
Frog
Xenopus laevis
Q6INI7
276
30746
Y216
A
R
D
E
K
A
S
Y
V
A
W
G
H
S
T
Zebra Danio
Brachydanio rerio
Q4VBV9
277
30347
Y216
A
R
D
E
T
A
S
Y
V
A
W
G
H
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76464
460
52213
R246
I
G
W
H
N
Q
K
R
Q
S
W
G
H
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76463
440
49917
R232
T
G
A
H
N
P
K
R
Q
S
Y
G
H
S
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309478
370
40453
Y305
A
R
D
V
A
A
G
Y
V
A
W
G
H
S
T
Maize
Zea mays
NP_001146295
362
38604
Y298
A
R
D
T
S
A
G
Y
V
A
W
G
H
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYF5
326
36438
G249
L
V
A
S
N
R
I
G
K
E
I
I
E
T
E
Baker's Yeast
Sacchar. cerevisiae
P49954
291
32531
Y232
A
R
N
L
Q
S
S
Y
H
A
Y
G
H
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.6
83.7
76.1
N.A.
89.4
88.4
N.A.
N.A.
81.1
78.9
74.3
N.A.
23.7
N.A.
26.3
N.A.
Protein Similarity:
100
66.6
84.3
81.4
N.A.
95.6
95.2
N.A.
N.A.
91.3
90.5
89.8
N.A.
37.8
N.A.
39.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
80
N.A.
26.6
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
44.8
44.2
N.A.
23.6
46.7
N.A.
Protein Similarity:
55.6
55.5
N.A.
39.2
67
N.A.
P-Site Identity:
80
80
N.A.
0
53.3
N.A.
P-Site Similarity:
80
80
N.A.
6.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
14
0
7
74
0
0
0
80
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
74
27
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
34
0
0
0
0
0
7
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
0
0
0
0
14
7
0
0
0
94
0
0
0
% G
% His:
0
0
0
14
0
0
0
0
7
0
0
0
94
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
7
7
0
0
7
% I
% Lys:
0
0
0
0
47
0
14
0
7
0
0
0
0
0
0
% K
% Leu:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% M
% Asn:
0
0
7
0
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
14
7
0
0
14
0
0
0
0
0
0
% Q
% Arg:
0
80
0
0
0
7
0
14
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
7
7
67
0
0
14
0
0
0
94
7
% S
% Thr:
7
0
0
7
7
0
0
0
0
0
0
0
0
7
67
% T
% Val:
0
7
0
7
0
0
0
0
74
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
80
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _