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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOSC5 All Species: 20.91
Human Site: S171 Identified Species: 38.33
UniProt: Q9NQT4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQT4 NP_064543.3 235 25249 S171 T L V L D P T S K Q E K E A R
Chimpanzee Pan troglodytes XP_001152170 235 25264 S171 T L V L D P T S K Q E K E A R
Rhesus Macaque Macaca mulatta XP_001102687 235 25292 S171 T L V L D P T S K Q E K E A R
Dog Lupus familis XP_852838 235 24945 A171 T L V L D P T A K Q E K E A R
Cat Felis silvestris
Mouse Mus musculus Q9CRA8 235 25175 T171 N L V L D P T T K Q E K E A R
Rat Rattus norvegicus NP_001100963 97 10638 K34 L V L D P T T K Q E K E A R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6P0I8 271 29438 Q201 A E E C G S W Q E G Y G D N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624485 223 24732 S159 N I I L D P D S T Q L Q D A K
Nematode Worm Caenorhab. elegans Q17533 240 26046 S170 K P I V D L T S R E E T D L L
Sea Urchin Strong. purpuratus XP_793149 185 19982 E122 L I M D P T K E Q T K D A E C
Poplar Tree Populus trichocarpa XP_002324223 243 26246 S174 T Y L V F P N S V V S V L P E
Maize Zea mays NP_001146469 240 26143 N175 F A H L V F P N S R K S V E S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53256 223 24389 A151 D I I V D P T A E Q L K I S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97.8 93.1 N.A. 89.3 37 N.A. N.A. N.A. N.A. 25.8 N.A. N.A. 37.4 28.7 37
Protein Similarity: 100 99.1 98.3 94.8 N.A. 92.7 39.1 N.A. N.A. N.A. N.A. 40.9 N.A. N.A. 61.7 46.6 54
P-Site Identity: 100 100 100 93.3 N.A. 86.6 6.6 N.A. N.A. N.A. N.A. 0 N.A. N.A. 40 26.6 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 46.6 N.A. N.A. N.A. N.A. 20 N.A. N.A. 73.3 60 26.6
Percent
Protein Identity: 40.7 37.5 N.A. N.A. 22.5 N.A.
Protein Similarity: 59.2 55.4 N.A. N.A. 40.8 N.A.
P-Site Identity: 20 6.6 N.A. N.A. 33.3 N.A.
P-Site Similarity: 33.3 26.6 N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 16 0 0 0 0 16 47 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 0 0 16 62 0 8 0 0 0 0 8 24 0 0 % D
% Glu: 0 8 8 0 0 0 0 8 16 16 47 8 39 16 8 % E
% Phe: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 8 0 8 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 24 24 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 0 0 0 0 0 8 8 39 0 24 47 0 0 8 % K
% Leu: 16 39 16 54 0 8 0 0 0 0 16 0 8 8 16 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 0 0 0 8 8 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 16 62 8 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 8 16 54 0 8 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 39 % R
% Ser: 0 0 0 0 0 8 0 47 8 0 8 8 0 8 8 % S
% Thr: 39 0 0 0 0 16 62 8 8 8 0 8 0 0 0 % T
% Val: 0 8 39 24 8 0 0 0 8 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _