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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC5
All Species:
20.3
Human Site:
S67
Identified Species:
37.22
UniProt:
Q9NQT4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT4
NP_064543.3
235
25249
S67
G
P
A
E
V
K
V
S
K
E
I
F
N
K
A
Chimpanzee
Pan troglodytes
XP_001152170
235
25264
S67
G
P
A
E
V
K
V
S
K
E
I
F
N
K
A
Rhesus Macaque
Macaca mulatta
XP_001102687
235
25292
S67
G
P
A
E
V
K
V
S
K
E
I
F
N
K
A
Dog
Lupus familis
XP_852838
235
24945
S67
G
P
A
E
V
K
V
S
K
E
I
F
N
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRA8
235
25175
S67
G
P
A
E
V
K
V
S
K
E
I
F
N
K
A
Rat
Rattus norvegicus
NP_001100963
97
10638
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
R81
G
P
K
E
T
E
R
R
D
E
T
D
M
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624485
223
24732
K71
E
V
S
Y
I
P
V
K
G
P
A
K
I
D
D
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
Q70
D
K
C
A
I
V
C
Q
Y
S
A
T
K
F
S
Sea Urchin
Strong. purpuratus
XP_793149
185
19982
V39
P
K
I
G
I
S
G
V
R
E
K
A
L
E
R
Poplar Tree
Populus trichocarpa
XP_002324223
243
26246
T70
E
V
I
W
K
P
K
T
G
Q
I
G
K
L
E
Maize
Zea mays
NP_001146469
240
26143
T72
E
V
V
W
K
P
K
T
G
Q
I
G
R
Q
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53256
223
24389
E67
T
T
R
E
K
V
L
E
D
K
L
R
A
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
97.8
93.1
N.A.
89.3
37
N.A.
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
37.4
28.7
37
Protein Similarity:
100
99.1
98.3
94.8
N.A.
92.7
39.1
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
N.A.
61.7
46.6
54
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
20
13.3
26.6
Percent
Protein Identity:
40.7
37.5
N.A.
N.A.
22.5
N.A.
Protein Similarity:
59.2
55.4
N.A.
N.A.
40.8
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
39
8
0
0
0
0
0
0
16
8
8
0
39
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
16
0
0
8
0
8
8
% D
% Glu:
24
0
0
54
0
8
0
8
0
54
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
39
0
8
0
% F
% Gly:
47
0
0
8
0
0
8
0
24
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
24
0
0
0
0
0
54
0
8
0
0
% I
% Lys:
0
16
8
0
24
39
16
8
39
8
8
8
16
47
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
8
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% N
% Pro:
8
47
0
0
0
24
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
16
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
0
8
8
8
0
0
8
8
0
8
% R
% Ser:
0
0
8
0
0
8
0
39
0
8
0
0
0
0
8
% S
% Thr:
8
8
0
0
8
0
0
16
0
0
8
8
0
0
8
% T
% Val:
0
24
8
0
39
16
47
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _