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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
10
Human Site:
S145
Identified Species:
15.71
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
S145
P
A
S
L
S
Y
L
S
F
E
G
A
T
K
R
Chimpanzee
Pan troglodytes
XP_520587
275
29580
S145
P
A
S
L
S
Y
L
S
F
E
G
A
T
K
R
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
S145
P
A
S
L
S
Y
L
S
F
E
G
A
T
K
R
Dog
Lupus familis
XP_538738
275
29530
A145
P
A
S
L
S
Y
L
A
F
E
G
A
T
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
A144
P
A
S
L
S
Y
L
A
F
E
G
A
T
K
R
Rat
Rattus norvegicus
NP_001101406
215
22475
V105
G
G
G
G
G
G
G
V
Y
W
V
D
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
A160
T
A
S
L
S
Y
L
A
F
E
G
A
T
K
R
Chicken
Gallus gallus
XP_421510
261
27779
A131
Q
A
S
L
S
Y
L
A
F
E
G
A
T
K
R
Frog
Xenopus laevis
NP_001089320
250
27223
K124
L
A
F
E
G
A
T
K
K
N
R
P
N
V
K
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
N123
F
E
G
A
T
K
R
N
R
P
N
V
Q
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
V122
G
D
L
I
Y
A
R
V
L
N
A
S
A
D
I
Honey Bee
Apis mellifera
XP_396758
241
26207
V125
L
V
F
A
K
L
L
V
A
S
K
D
M
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
V123
N
V
Q
V
G
D
V
V
Y
A
K
L
L
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
L126
K
F
E
V
S
T
L
L
Y
T
R
V
V
K
T
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
T125
L
V
Y
A
R
V
C
T
A
E
K
E
L
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
86.6
86.6
6.6
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
93.3
93.3
13.3
13.3
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
20
0
14
0
27
14
7
7
47
7
0
14
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
0
0
14
0
7
0
% D
% Glu:
0
7
7
7
0
0
0
0
0
54
0
7
0
14
0
% E
% Phe:
7
7
14
0
0
0
0
0
47
0
0
0
0
0
0
% F
% Gly:
14
7
14
7
20
7
7
0
0
0
47
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
7
0
0
0
7
7
0
7
7
0
20
0
0
54
7
% K
% Leu:
20
0
7
47
0
7
60
7
7
0
0
7
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
7
0
14
7
0
7
0
0
% N
% Pro:
34
0
0
0
0
0
0
0
0
7
0
7
0
0
7
% P
% Gln:
7
0
7
0
0
0
0
0
0
0
0
0
7
7
7
% Q
% Arg:
0
0
0
0
7
0
14
0
7
0
14
0
0
0
47
% R
% Ser:
0
0
47
0
54
0
0
20
0
7
0
7
7
0
0
% S
% Thr:
7
0
0
0
7
7
7
7
0
7
0
0
47
0
7
% T
% Val:
0
20
0
14
0
7
7
27
0
0
7
14
7
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
47
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _