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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
9.7
Human Site:
S15
Identified Species:
15.24
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
S15
A
A
E
S
L
A
G
S
R
A
R
A
A
R
T
Chimpanzee
Pan troglodytes
XP_520587
275
29580
S15
A
A
E
S
L
A
G
S
R
A
R
A
A
R
T
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
S15
A
A
E
Y
L
A
G
S
R
A
R
A
A
R
T
Dog
Lupus familis
XP_538738
275
29530
D15
A
A
E
S
L
P
G
D
R
A
R
A
A
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
C15
G
P
E
S
V
A
G
C
R
A
R
A
V
H
K
Rat
Rattus norvegicus
NP_001101406
215
22475
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
R48
A
A
Q
A
R
L
D
R
L
V
V
A
G
E
E
Chicken
Gallus gallus
XP_421510
261
27779
Q15
P
A
E
S
R
V
G
Q
V
V
L
P
G
D
V
Frog
Xenopus laevis
NP_001089320
250
27223
L15
D
V
V
G
Q
I
V
L
P
G
D
V
L
V
L
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
D15
S
L
L
E
R
I
G
D
V
V
L
P
G
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
I14
I
V
M
P
G
E
R
I
A
A
I
E
E
L
A
Honey Bee
Apis mellifera
XP_396758
241
26207
I15
V
V
M
P
G
D
T
I
K
D
I
T
I
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
P15
F
E
P
R
V
V
L
P
G
D
S
L
M
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
Q15
S
P
T
S
L
I
D
Q
T
V
V
P
G
D
V
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
T16
D
S
F
P
V
D
P
T
T
P
V
K
L
G
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
100
93.3
86.6
N.A.
53.3
0
N.A.
20
26.6
0
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
60
0
N.A.
33.3
26.6
0
13.3
N.A.
6.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
40
0
7
0
27
0
0
7
40
0
40
27
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
14
14
14
0
14
7
0
0
20
0
% D
% Glu:
0
7
40
7
0
7
0
0
0
0
0
7
7
7
7
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
14
0
47
0
7
7
0
0
27
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% H
% Ile:
7
0
0
0
0
20
0
14
0
0
14
0
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% K
% Leu:
0
7
7
0
34
7
7
7
7
0
14
7
14
7
14
% L
% Met:
0
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
7
14
7
20
0
7
7
7
7
7
0
20
0
0
7
% P
% Gln:
0
0
7
0
7
0
0
14
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
20
0
7
7
34
0
34
0
0
27
0
% R
% Ser:
14
7
0
40
0
0
0
20
0
0
7
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
7
7
14
0
0
7
0
0
27
% T
% Val:
7
20
7
0
20
14
7
0
14
27
20
7
7
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _