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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
11.21
Human Site:
S54
Identified Species:
17.62
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
S54
G
A
V
E
R
P
L
S
L
N
A
R
A
C
S
Chimpanzee
Pan troglodytes
XP_520587
275
29580
S54
G
A
V
E
R
P
L
S
L
N
A
G
A
R
S
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
S54
G
A
G
E
R
P
L
S
L
N
A
G
A
R
S
Dog
Lupus familis
XP_538738
275
29530
R54
G
P
G
E
R
P
L
R
L
N
A
G
T
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
R54
G
A
G
E
Q
P
L
R
L
N
A
G
A
R
P
Rat
Rattus norvegicus
NP_001101406
215
22475
A19
E
S
V
A
G
C
R
A
R
A
V
H
K
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
L72
G
G
G
D
E
R
R
L
L
P
E
R
G
R
A
Chicken
Gallus gallus
XP_421510
261
27779
P37
E
Q
D
T
E
R
L
P
L
G
T
S
A
A
P
Frog
Xenopus laevis
NP_001089320
250
27223
S38
L
S
L
S
G
P
S
S
T
N
R
S
R
V
V
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
K37
E
A
G
D
A
N
P
K
A
D
R
L
I
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
D36
G
P
G
L
R
R
L
D
D
T
V
V
A
S
K
Honey Bee
Apis mellifera
XP_396758
241
26207
T39
G
L
R
R
E
A
D
T
V
F
A
Y
K
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
L37
K
I
T
L
G
P
G
L
R
Q
D
E
T
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
S38
N
Q
T
I
K
L
G
S
G
L
R
Q
D
N
E
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
N38
T
Q
E
I
R
P
V
N
T
G
V
L
H
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
86.6
80
60
N.A.
60
6.6
N.A.
20
20
20
13.3
N.A.
26.6
13.3
N.A.
6.6
P-Site Similarity:
100
86.6
80
60
N.A.
66.6
20
N.A.
33.3
20
33.3
26.6
N.A.
26.6
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
7
7
7
0
7
7
7
40
0
40
14
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
14
0
% C
% Asp:
0
0
7
14
0
0
7
7
7
7
7
0
7
0
0
% D
% Glu:
20
0
7
34
20
0
0
0
0
0
7
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
54
7
40
0
20
0
14
0
7
14
0
27
7
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% H
% Ile:
0
7
0
14
0
0
0
0
0
0
0
0
7
0
7
% I
% Lys:
7
0
0
0
7
0
0
7
0
0
0
0
14
7
7
% K
% Leu:
7
7
7
14
0
7
47
14
47
7
0
14
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
0
7
0
40
0
0
0
7
0
% N
% Pro:
0
14
0
0
0
54
7
7
0
7
0
0
0
0
14
% P
% Gln:
0
20
0
0
7
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
0
7
7
40
20
14
14
14
0
20
14
7
34
0
% R
% Ser:
0
14
0
7
0
0
7
34
0
0
0
14
0
7
34
% S
% Thr:
7
0
14
7
0
0
0
7
14
7
7
0
14
0
0
% T
% Val:
0
0
20
0
0
0
7
0
7
0
20
7
0
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _