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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
11.21
Human Site:
S93
Identified Species:
17.62
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
S93
L
R
H
K
E
P
G
S
G
S
G
G
G
V
Y
Chimpanzee
Pan troglodytes
XP_520587
275
29580
S93
L
R
H
K
E
P
G
S
G
S
E
G
G
V
Y
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
S93
L
R
H
K
E
P
G
S
G
S
G
G
G
V
Y
Dog
Lupus familis
XP_538738
275
29530
G93
L
R
H
K
E
P
G
G
G
S
G
G
G
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
S92
R
L
R
H
K
E
P
S
G
G
G
G
G
V
Y
Rat
Rattus norvegicus
NP_001101406
215
22475
Q53
G
L
G
G
P
G
E
Q
P
L
R
L
N
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
G108
L
L
R
R
R
P
G
G
A
A
G
F
G
M
Y
Chicken
Gallus gallus
XP_421510
261
27779
A79
R
R
A
G
D
G
A
A
A
A
A
G
G
A
Y
Frog
Xenopus laevis
NP_001089320
250
27223
V72
L
R
H
R
D
P
A
V
Y
W
V
D
S
Q
Q
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
W71
H
K
Q
P
N
M
Y
W
V
N
C
Q
Q
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
D70
R
Y
I
P
A
R
G
D
L
I
L
G
I
V
R
Honey Bee
Apis mellifera
XP_396758
241
26207
V73
V
P
N
R
G
E
H
V
V
G
I
V
T
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
P71
C
H
Q
K
R
Y
V
P
A
K
G
D
K
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
P74
S
S
H
K
R
Y
V
P
R
P
E
D
H
V
L
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
I73
P
S
V
N
D
F
V
I
G
V
I
I
G
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
93.3
100
93.3
N.A.
46.6
0
N.A.
40
26.6
26.6
0
N.A.
20
0
N.A.
20
P-Site Similarity:
100
93.3
100
93.3
N.A.
53.3
0
N.A.
60
46.6
40
13.3
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
14
7
20
14
7
0
0
14
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
7
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
0
27
14
7
0
0
0
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
7
% F
% Gly:
7
0
7
14
7
14
40
14
40
14
40
47
54
0
7
% G
% His:
7
7
40
7
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
7
14
7
7
0
0
% I
% Lys:
0
7
0
40
7
0
0
0
0
7
0
0
7
0
7
% K
% Leu:
40
20
0
0
0
0
0
0
7
7
7
7
0
0
14
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
7
7
7
0
0
0
0
7
0
0
7
0
0
% N
% Pro:
7
7
0
14
7
40
7
14
7
7
0
0
0
0
0
% P
% Gln:
0
0
14
0
0
0
0
7
0
0
0
7
7
14
7
% Q
% Arg:
20
40
14
20
20
7
0
0
7
0
7
0
0
7
14
% R
% Ser:
7
14
0
0
0
0
0
27
0
27
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% T
% Val:
7
0
7
0
0
0
20
14
14
7
7
7
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
14
7
0
7
0
0
0
0
0
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _