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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
24.24
Human Site:
Y100
Identified Species:
38.1
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
Y100
S
G
S
G
G
G
V
Y
W
V
D
S
Q
Q
K
Chimpanzee
Pan troglodytes
XP_520587
275
29580
Y100
S
G
S
E
G
G
V
Y
W
V
D
S
Q
Q
K
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
Y100
S
G
S
G
G
G
V
Y
W
V
D
S
Q
Q
K
Dog
Lupus familis
XP_538738
275
29530
Y100
G
G
S
G
G
G
V
Y
W
V
D
S
Q
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
Y99
S
G
G
G
G
G
V
Y
W
V
D
S
Q
Q
K
Rat
Rattus norvegicus
NP_001101406
215
22475
G60
Q
P
L
R
L
N
A
G
A
R
P
R
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
Y115
G
A
A
G
F
G
M
Y
W
V
D
S
S
Q
K
Chicken
Gallus gallus
XP_421510
261
27779
Y86
A
A
A
A
G
G
A
Y
W
V
D
S
Q
Q
K
Frog
Xenopus laevis
NP_001089320
250
27223
Q79
V
Y
W
V
D
S
Q
Q
K
R
Y
V
P
V
K
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
R78
W
V
N
C
Q
Q
R
R
Y
V
P
A
K
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
R77
D
L
I
L
G
I
V
R
A
K
A
G
D
L
Y
Honey Bee
Apis mellifera
XP_396758
241
26207
K80
V
V
G
I
V
T
Q
K
G
G
D
I
F
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
L78
P
A
K
G
D
K
V
L
G
V
V
T
Q
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
L81
P
R
P
E
D
H
V
L
G
I
V
V
D
C
K
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
F80
I
G
V
I
I
G
T
F
S
D
S
Y
K
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
93.3
100
93.3
N.A.
93.3
0
N.A.
60
66.6
6.6
6.6
N.A.
13.3
6.6
N.A.
26.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
6.6
N.A.
73.3
80
6.6
40
N.A.
13.3
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
14
7
0
0
14
0
14
0
7
7
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
0
0
20
0
0
0
0
7
54
0
14
0
0
% D
% Glu:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% F
% Gly:
14
40
14
40
47
54
0
7
20
7
0
7
0
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
14
7
7
0
0
0
7
0
7
0
0
7
% I
% Lys:
0
0
7
0
0
7
0
7
7
7
0
0
14
14
60
% K
% Leu:
0
7
7
7
7
0
0
14
0
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
14
7
7
0
0
0
0
0
0
0
14
0
7
0
0
% P
% Gln:
7
0
0
0
7
7
14
7
0
0
0
0
47
47
0
% Q
% Arg:
0
7
0
7
0
0
7
14
0
14
0
7
0
7
0
% R
% Ser:
27
0
27
0
0
7
0
0
7
0
7
47
7
0
7
% S
% Thr:
0
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% T
% Val:
14
14
7
7
7
0
54
0
0
60
14
14
0
14
7
% V
% Trp:
7
0
7
0
0
0
0
0
47
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
47
7
0
7
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _