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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC3
All Species:
26.97
Human Site:
Y109
Identified Species:
42.38
UniProt:
Q9NQT5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQT5
NP_001002269.1
275
29572
Y109
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Chimpanzee
Pan troglodytes
XP_520587
275
29580
Y109
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Rhesus Macaque
Macaca mulatta
XP_001114719
275
29570
Y109
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Dog
Lupus familis
XP_538738
275
29530
Y109
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK4
274
29528
Y108
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Rat
Rattus norvegicus
NP_001101406
215
22475
C69
R
P
R
L
R
I
V
C
G
P
G
L
R
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511305
290
31757
Y124
V
D
S
S
Q
K
R
Y
V
P
V
K
G
D
H
Chicken
Gallus gallus
XP_421510
261
27779
Y95
V
D
S
Q
Q
K
R
Y
V
P
V
K
G
D
H
Frog
Xenopus laevis
NP_001089320
250
27223
D88
R
Y
V
P
V
K
G
D
H
V
I
G
I
V
T
Zebra Danio
Brachydanio rerio
NP_001025132
247
26803
V87
V
P
A
K
G
E
S
V
I
G
I
V
T
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722725
232
25008
V86
K
A
G
D
L
Y
R
V
D
I
G
A
T
D
T
Honey Bee
Apis mellifera
XP_396758
241
26207
I89
G
D
I
F
K
V
D
I
G
A
S
E
Q
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781285
245
26968
D87
V
V
T
Q
K
A
G
D
V
F
R
V
D
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565592
241
26461
E90
I
V
V
D
C
K
G
E
N
Y
W
I
D
I
K
Baker's Yeast
Sacchar. cerevisiae
Q08285
240
26572
Q89
D
S
Y
K
V
S
L
Q
N
F
S
S
S
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
92.7
N.A.
87.2
65.4
N.A.
65.5
69.8
63.2
58.1
N.A.
39.2
42.1
N.A.
46.1
Protein Similarity:
100
98.9
98.1
94.5
N.A.
92
68.3
N.A.
75.5
79.2
77.4
74.1
N.A.
61.4
62.1
N.A.
62.9
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
100
6.6
6.6
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
100
13.3
40
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
0
0
7
0
7
0
14
0
% A
% Cys:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
7
54
0
14
0
0
7
14
7
0
0
0
14
54
0
% D
% Glu:
0
0
0
0
0
7
0
7
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
14
0
0
0
0
0
% F
% Gly:
7
0
7
0
7
0
20
0
14
7
14
7
47
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
47
% H
% Ile:
7
0
7
0
0
7
0
7
7
7
14
7
7
14
0
% I
% Lys:
7
0
0
14
14
60
0
0
0
0
0
47
0
0
14
% K
% Leu:
0
0
0
7
7
0
7
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% N
% Pro:
0
14
0
7
0
0
0
0
0
54
0
0
0
0
0
% P
% Gln:
0
0
0
47
47
0
0
7
0
0
0
0
7
0
0
% Q
% Arg:
14
0
7
0
7
0
54
0
0
0
7
0
7
7
0
% R
% Ser:
0
7
47
7
0
7
7
0
0
0
14
7
7
0
14
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
14
0
14
% T
% Val:
60
14
14
0
14
7
7
14
54
7
47
14
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
7
0
0
7
0
47
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _