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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 20.61
Human Site: S113 Identified Species: 32.38
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S113 T S R R R A Q S L G L L G D E
Chimpanzee Pan troglodytes XP_510301 627 67581 A92 T N R R G M K A A K H G S E E
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S113 T S R R R A Q S L G L L G D E
Dog Lupus familis XP_544614 968 105825 S400 T S R R R A Q S L G L L G D E
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 L114 S R R R A Q S L G L L G D D Q
Rat Rattus norvegicus Q62829 544 60692 E9 S D S L D N E E K P P A P P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 S104 S N T L R G R S P P S R R R A
Chicken Gallus gallus XP_426393 667 74767 S113 T S R R R A Q S L G L L G E D
Frog Xenopus laevis NP_001082100 650 73749 Q108 R R E S P P C Q P R E D R F H
Zebra Danio Brachydanio rerio XP_001919719 693 77347 S113 S A R K R A Q S L G R L G E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 M104 M M G S M A P M N P M A P G A
Honey Bee Apis mellifera XP_001122147 624 70155 G89 P K G R T F S G E K N T E N G
Nematode Worm Caenorhab. elegans Q17850 572 63863 E37 G L K P L P K E P E A T K K K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 P264 K S F P S K N P L K N S S P P
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 T262 K S T I S N K T M G A S S F R
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 26.6 100 100 N.A. 26.6 0 N.A. 13.3 86.6 0 60 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 53.3 100 100 N.A. 40 13.3 N.A. 33.3 100 0 86.6 N.A. 13.3 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 40 0 7 7 0 14 14 0 0 14 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 0 0 0 0 0 0 7 7 27 7 % D
% Glu: 0 0 7 0 0 0 7 14 7 7 7 0 7 20 27 % E
% Phe: 0 0 7 0 0 7 0 0 0 0 0 0 0 14 0 % F
% Gly: 7 0 14 0 7 7 0 7 7 40 0 14 34 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 14 7 7 7 0 7 20 0 7 20 0 0 7 7 7 % K
% Leu: 0 7 0 14 7 0 0 7 40 7 34 34 0 0 14 % L
% Met: 7 7 0 0 7 7 0 7 7 0 7 0 0 0 0 % M
% Asn: 0 14 0 0 0 14 7 0 7 0 14 0 0 7 0 % N
% Pro: 7 0 0 14 7 14 7 7 20 20 7 0 14 14 7 % P
% Gln: 0 0 0 0 0 7 34 7 0 0 0 0 0 0 7 % Q
% Arg: 7 14 47 47 40 0 7 0 0 7 7 7 14 7 7 % R
% Ser: 27 40 7 14 14 0 14 40 0 0 7 14 20 0 0 % S
% Thr: 34 0 14 0 7 0 0 7 0 0 0 14 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _