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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
15.76
Human Site:
S224
Identified Species:
24.76
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S224
M
K
A
A
K
H
G
S
E
E
A
R
P
Q
S
Chimpanzee
Pan troglodytes
XP_510301
627
67581
W203
K
R
L
L
T
V
A
W
P
N
S
S
F
R
P
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S224
M
K
A
A
K
H
G
S
E
E
A
R
P
Q
S
Dog
Lupus familis
XP_544614
968
105825
S511
T
K
A
P
R
H
G
S
E
E
A
R
P
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S225
V
K
V
A
K
H
S
S
E
E
A
R
P
Q
S
Rat
Rattus norvegicus
Q62829
544
60692
L120
K
K
N
P
Q
A
V
L
D
V
L
K
F
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
P215
R
S
S
D
E
R
R
P
Q
S
C
L
V
A
R
Chicken
Gallus gallus
XP_426393
667
74767
P224
S
E
E
C
W
P
Q
P
C
L
V
R
Q
A
N
Frog
Xenopus laevis
NP_001082100
650
73749
E219
V
V
K
R
D
K
G
E
E
K
R
P
K
S
A
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
E224
G
D
I
G
S
P
T
E
R
L
M
M
R
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q215
P
L
A
V
R
T
D
Q
T
N
L
Q
Q
Y
R
Honey Bee
Apis mellifera
XP_001122147
624
70155
G200
S
P
N
L
T
H
V
G
S
N
A
P
N
L
S
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
T148
I
D
D
A
P
S
R
T
P
S
Y
G
L
K
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S375
L
L
T
S
S
G
I
S
K
R
E
Q
Q
Q
N
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E373
I
S
E
S
G
I
T
E
K
D
R
R
E
H
P
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
80
N.A.
80
6.6
N.A.
0
6.6
13.3
0
N.A.
6.6
20
6.6
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
86.6
26.6
N.A.
20
20
33.3
6.6
N.A.
20
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
27
27
0
7
7
0
0
0
34
0
0
14
7
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
7
0
0
0
0
% C
% Asp:
0
14
7
7
7
0
7
0
7
7
0
0
0
0
7
% D
% Glu:
0
7
14
0
7
0
0
20
34
27
7
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% F
% Gly:
7
0
0
7
7
7
27
7
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
34
0
0
0
0
0
0
0
7
0
% H
% Ile:
14
0
7
0
0
7
7
0
0
0
0
0
0
0
0
% I
% Lys:
14
34
7
0
20
7
0
0
14
7
0
7
7
7
0
% K
% Leu:
7
14
7
14
0
0
0
7
0
14
14
7
7
7
0
% L
% Met:
14
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
0
0
14
0
0
0
0
0
0
20
0
0
7
0
14
% N
% Pro:
7
7
0
14
7
14
0
14
14
0
0
14
27
0
20
% P
% Gln:
0
0
0
0
7
0
7
7
7
0
0
14
20
34
0
% Q
% Arg:
7
7
0
7
14
7
14
0
7
7
14
40
7
14
14
% R
% Ser:
14
14
7
14
14
7
7
34
7
14
7
7
0
7
34
% S
% Thr:
7
0
7
0
14
7
14
7
7
0
0
0
0
0
0
% T
% Val:
14
7
7
7
0
7
14
0
0
7
7
0
7
0
0
% V
% Trp:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _