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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 8.48
Human Site: S301 Identified Species: 13.33
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S301 P Q K D N P P S L V A K A Q S
Chimpanzee Pan troglodytes XP_510301 627 67581 N280 H A Q I S T S N L Y L P Q D P
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S301 P Q K D N P P S L V A K A Q S
Dog Lupus familis XP_544614 968 105825 S588 Q Q K D P P P S L V A K A Q S
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 N302 P Q K D S S S N L V A K A Q S
Rat Rattus norvegicus Q62829 544 60692 H197 V I A P R P E H T K S I Y T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 P292 L P S A E P D P A S A Y P S S
Chicken Gallus gallus XP_426393 667 74767 Q301 A Q S L P P D Q P T S D F P R
Frog Xenopus laevis NP_001082100 650 73749 L296 D S R S T V P L D S K S S V S
Zebra Danio Brachydanio rerio XP_001919719 693 77347 F301 G M R P P A G F L H S G T S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 N292 Q G G D Q N Q N P L H P H A H
Honey Bee Apis mellifera XP_001122147 624 70155 P277 T L L H K L Q P K I S P V G S
Nematode Worm Caenorhab. elegans Q17850 572 63863 D225 P H G E T P A D I V P P A I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 N452 R T G T P M S N H V M S P T L
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 F450 S P P A S P R F P Q V G H E G
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 6.6 100 86.6 N.A. 73.3 6.6 N.A. 20 13.3 13.3 13.3 N.A. 6.6 6.6 26.6 N.A.
P-Site Similarity: 100 26.6 100 86.6 N.A. 86.6 13.3 N.A. 20 20 26.6 26.6 N.A. 20 20 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 14 0 7 7 0 7 0 34 0 34 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 34 0 0 14 7 7 0 0 7 0 7 0 % D
% Glu: 0 0 0 7 7 0 7 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 14 0 0 0 0 7 0 0 % F
% Gly: 7 7 20 0 0 0 7 0 0 0 0 14 0 7 7 % G
% His: 7 7 0 7 0 0 0 7 7 7 7 0 14 0 7 % H
% Ile: 0 7 0 7 0 0 0 0 7 7 0 7 0 7 0 % I
% Lys: 0 0 27 0 7 0 0 0 7 7 7 27 0 0 0 % K
% Leu: 7 7 7 7 0 7 0 7 40 7 7 0 0 0 7 % L
% Met: 0 7 0 0 0 7 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 14 7 0 27 0 0 0 0 0 0 0 % N
% Pro: 27 14 7 14 27 54 27 14 20 0 7 27 14 7 14 % P
% Gln: 14 34 7 0 7 0 14 7 0 7 0 0 7 27 0 % Q
% Arg: 7 0 14 0 7 0 7 0 0 0 0 0 0 0 14 % R
% Ser: 7 7 14 7 20 7 20 20 0 14 27 14 7 14 54 % S
% Thr: 7 7 0 7 14 7 0 0 7 7 0 0 7 14 0 % T
% Val: 7 0 0 0 0 7 0 0 0 40 7 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _