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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 16.67
Human Site: S328 Identified Species: 26.19
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S328 L T T S D T S S P Q K S L R T
Chimpanzee Pan troglodytes XP_510301 627 67581 F307 G V V T H E Q F K A A L R M V
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S328 L T T S D T S S P Q K S L R T
Dog Lupus familis XP_544614 968 105825 S615 L T S Q D T S S P Q K S L R T
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 S329 L T T S D T S S P Q K S L R T
Rat Rattus norvegicus Q62829 544 60692 S224 N K E A T P P S A E N A N S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 P319 A G S P R T R P A P A N A S G
Chicken Gallus gallus XP_426393 667 74767 V328 T A E K A I A V P Q G R P S P
Frog Xenopus laevis NP_001082100 650 73749 H323 P K P P E K P H P T Q L A P H
Zebra Danio Brachydanio rerio XP_001919719 693 77347 L328 R S S C S Y T L G L S P N I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S319 A S R A S S S S G G A S S A A
Honey Bee Apis mellifera XP_001122147 624 70155 Q304 H N V N K Y S Q S A L S S G N
Nematode Worm Caenorhab. elegans Q17850 572 63863 I252 P K E E E E K I P D L S K G Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 P479 P S R P A P K P P S S A S A S
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 A477 K G P G P L P A K D I N L I P
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 86.6 N.A. 100 6.6 N.A. 6.6 13.3 6.6 0 N.A. 20 13.3 13.3 N.A.
P-Site Similarity: 100 6.6 100 93.3 N.A. 100 33.3 N.A. 20 20 20 26.6 N.A. 40 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 14 14 0 7 7 14 14 20 14 14 14 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 27 0 0 0 0 14 0 0 0 0 0 % D
% Glu: 0 0 20 7 14 14 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 7 14 0 7 0 0 0 0 14 7 7 0 0 14 7 % G
% His: 7 0 0 0 7 0 0 7 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 7 0 7 0 0 7 0 0 14 0 % I
% Lys: 7 20 0 7 7 7 14 0 14 0 27 0 7 0 0 % K
% Leu: 27 0 0 0 0 7 0 7 0 7 14 14 34 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 7 0 7 0 0 0 0 0 0 7 14 14 0 7 % N
% Pro: 20 0 14 20 7 14 20 14 54 7 0 7 7 7 14 % P
% Gln: 0 0 0 7 0 0 7 7 0 34 7 0 0 0 7 % Q
% Arg: 7 0 14 0 7 0 7 0 0 0 0 7 7 27 0 % R
% Ser: 0 20 20 20 14 7 40 40 7 7 14 47 20 20 20 % S
% Thr: 7 27 20 7 7 34 7 0 0 7 0 0 0 0 27 % T
% Val: 0 7 14 0 0 0 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _