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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 31.21
Human Site: S605 Identified Species: 49.05
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 S605 E P P Y F S D S P V Q A M K R
Chimpanzee Pan troglodytes XP_510301 627 67581 Q557 P S T P K T T Q K Q L G N W Q
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 S605 E P P Y F S D S P V Q A M K R
Dog Lupus familis XP_544614 968 105825 S892 E P P Y F S D S P V Q A M K R
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 S606 E P P Y F S D S P V Q A M K R
Rat Rattus norvegicus Q62829 544 60692 I474 P L R A L Y L I A T N G T P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 S569 A M K R L R D S P P P K M R N
Chicken Gallus gallus XP_426393 667 74767 S591 E P P Y F S D S P V Q A M K R
Frog Xenopus laevis NP_001082100 650 73749 P578 E P P Y F N E P P L K A M K M
Zebra Danio Brachydanio rerio XP_001919719 693 77347 T617 E P P Y F S E T P V A A M K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 Q569 F F N E P P L Q A M R R I R D
Honey Bee Apis mellifera XP_001122147 624 70155 A554 F N E P P L Q A M R R I R D M
Nematode Worm Caenorhab. elegans Q17850 572 63863 A502 L R A I Y L I A T N G K P D F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 T818 E P P Y L N E T P L R A L Y L
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 S872 E P P Y L T E S P L R A L W L
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 26.6 100 60 80 N.A. 0 0 0 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 0 N.A. 33.3 100 86.6 93.3 N.A. 26.6 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 40 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 0 0 14 14 0 7 60 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 40 0 0 0 0 0 0 14 7 % D
% Glu: 60 0 7 7 0 0 27 0 0 0 0 0 0 0 7 % E
% Phe: 14 7 0 0 47 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 7 14 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 7 7 0 0 0 7 7 0 0 % I
% Lys: 0 0 7 0 7 0 0 0 7 0 7 14 0 47 0 % K
% Leu: 7 7 0 0 27 14 14 0 0 20 7 0 14 0 14 % L
% Met: 0 7 0 0 0 0 0 0 7 7 0 0 54 0 14 % M
% Asn: 0 7 7 0 0 14 0 0 0 7 7 0 7 0 7 % N
% Pro: 14 60 60 14 14 7 0 7 67 7 7 0 7 7 0 % P
% Gln: 0 0 0 0 0 0 7 14 0 7 34 0 0 0 7 % Q
% Arg: 0 7 7 7 0 7 0 0 0 7 27 7 7 14 40 % R
% Ser: 0 7 0 0 0 40 0 47 0 0 0 0 0 0 0 % S
% Thr: 0 0 7 0 0 14 7 14 7 7 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % W
% Tyr: 0 0 0 60 7 7 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _