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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 16.97
Human Site: T271 Identified Species: 26.67
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 T271 M F L S T A A T A P P S S S K
Chimpanzee Pan troglodytes XP_510301 627 67581 L250 T S S P Q K S L R T A P A T G
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 T271 M F L S T A A T A P P S S S K
Dog Lupus familis XP_544614 968 105825 T558 M F L S T P A T A P A S S S K
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 T272 M F L S T P A T G A A S S S K
Rat Rattus norvegicus Q62829 544 60692 A167 T A S E P P L A P P V S E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 S262 R P G S K L Q S Q P V P C R R
Chicken Gallus gallus XP_426393 667 74767 L271 S N K S G P S L H I K P T A F
Frog Xenopus laevis NP_001082100 650 73749 G266 V V K Q T E T G R P F N T Y P
Zebra Danio Brachydanio rerio XP_001919719 693 77347 R271 P D M R S A N R L L V H P Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 G262 H T N N G N S G G S Y P P M Y
Honey Bee Apis mellifera XP_001122147 624 70155 S247 N T Q I S I T S G H I M E M L
Nematode Worm Caenorhab. elegans Q17850 572 63863 P195 Y N S K Q G V P P T T F S V N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S422 L P G S P Q V S T P P A N S F
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 T420 D F R S P P V T G T A P L V L
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 0 100 86.6 N.A. 73.3 13.3 N.A. 13.3 6.6 13.3 6.6 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 20 100 86.6 N.A. 73.3 20 N.A. 26.6 26.6 33.3 20 N.A. 13.3 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 20 27 7 20 7 27 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 7 0 0 0 0 0 0 14 7 7 % E
% Phe: 0 34 0 0 0 0 0 0 0 0 7 7 0 0 14 % F
% Gly: 0 0 14 0 14 7 0 14 27 0 0 0 0 0 7 % G
% His: 7 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 0 0 7 7 0 0 0 0 % I
% Lys: 0 0 14 7 7 7 0 0 0 0 7 0 0 0 27 % K
% Leu: 7 0 27 0 0 7 7 14 7 7 0 0 7 0 14 % L
% Met: 27 0 7 0 0 0 0 0 0 0 0 7 0 14 0 % M
% Asn: 7 14 7 7 0 7 7 0 0 0 0 7 7 0 14 % N
% Pro: 7 14 0 7 20 34 0 7 14 47 20 34 14 0 7 % P
% Gln: 0 0 7 7 14 7 7 0 7 0 0 0 0 7 0 % Q
% Arg: 7 0 7 7 0 0 0 7 14 0 0 0 0 7 7 % R
% Ser: 7 7 20 54 14 0 20 20 0 7 0 34 34 34 0 % S
% Thr: 14 14 0 0 34 0 14 34 7 20 7 0 14 7 0 % T
% Val: 7 7 0 0 0 0 20 0 0 0 20 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 7 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _