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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 15.15
Human Site: Y410 Identified Species: 23.81
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 Y410 P R L L L D S Y V K I G E G S
Chimpanzee Pan troglodytes XP_510301 627 67581 L381 G G T Q T G A L G M G S E Q P
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 Y410 P R L L L D S Y V K I G E G S
Dog Lupus familis XP_544614 968 105825 Y697 P R M L L D S Y V K I G E G S
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 Y411 P R L L L D S Y V K I G E G S
Rat Rattus norvegicus Q62829 544 60692 Q298 G Q E V A I K Q M N L Q Q Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 Q393 V C L A R E R Q S G R Q V A V
Chicken Gallus gallus XP_426393 667 74767 A410 S T G I V C I A R E K H S G R
Frog Xenopus laevis NP_001082100 650 73749 T398 T G I V C I A T I K S S G K L
Zebra Danio Brachydanio rerio XP_001919719 693 77347 F422 P R S Y L E N F V K I G E G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 Q393 T D K S T G R Q V A V K K M D
Honey Bee Apis mellifera XP_001122147 624 70155 V378 E K N T N R Q V A V K K M D L
Nematode Worm Caenorhab. elegans Q17850 572 63863 M326 A E V A I K Q M N L K D Q P K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 L623 P S T K Y A N L V K I G Q G A
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 F677 P R E I Y R G F T K I G Q G A
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 100 0 N.A. 6.6 6.6 6.6 66.6 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 33.3 N.A. 13.3 26.6 33.3 86.6 N.A. 20 6.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 40 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 14 7 7 14 7 7 7 0 0 0 7 14 % A
% Cys: 0 7 0 0 7 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 27 0 0 0 0 0 7 0 7 7 % D
% Glu: 7 7 14 0 0 14 0 0 0 7 0 0 40 0 0 % E
% Phe: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % F
% Gly: 14 14 7 0 0 14 7 0 7 7 7 47 7 54 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 14 7 14 7 0 7 0 47 0 0 0 0 % I
% Lys: 0 7 7 7 0 7 7 0 0 54 20 14 7 7 7 % K
% Leu: 0 0 27 27 34 0 0 14 0 7 7 0 0 0 14 % L
% Met: 0 0 7 0 0 0 0 7 7 7 0 0 7 7 0 % M
% Asn: 0 0 7 0 7 0 14 0 7 7 0 0 0 0 0 % N
% Pro: 47 0 0 0 0 0 0 0 0 0 0 0 0 7 14 % P
% Gln: 0 7 0 7 0 0 14 20 0 0 0 14 27 14 0 % Q
% Arg: 0 40 0 0 7 14 14 0 7 0 7 0 0 0 7 % R
% Ser: 7 7 7 7 0 0 27 0 7 0 7 14 7 0 34 % S
% Thr: 14 7 14 7 14 0 0 7 7 0 0 0 0 0 0 % T
% Val: 7 0 7 14 7 0 0 7 47 7 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 14 0 0 27 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _