KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
36.36
Human Site:
Y566
Identified Species:
57.14
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
Y566
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Chimpanzee
Pan troglodytes
XP_510301
627
67581
K518
G
F
C
A
Q
I
S
K
D
V
P
K
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
Y566
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Dog
Lupus familis
XP_544614
968
105825
Y853
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
Y567
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Rat
Rattus norvegicus
Q62829
544
60692
T435
W
M
A
P
E
V
V
T
R
K
A
Y
G
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
P530
P
E
V
I
S
R
T
P
Y
T
T
E
V
D
I
Chicken
Gallus gallus
XP_426393
667
74767
Y552
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Frog
Xenopus laevis
NP_001082100
650
73749
Y539
K
S
L
V
G
T
P
Y
W
M
A
P
E
L
I
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
Y578
K
S
L
V
G
T
P
Y
W
M
A
P
E
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S530
V
G
T
P
Y
W
M
S
P
E
V
I
S
R
L
Honey Bee
Apis mellifera
XP_001122147
624
70155
P515
G
T
P
Y
W
M
S
P
E
V
I
S
R
L
P
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
R463
M
A
P
E
V
V
T
R
K
Q
Y
G
P
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
Y779
T
T
M
V
G
T
P
Y
W
M
A
P
E
V
V
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
Y833
T
T
M
V
G
T
P
Y
W
M
A
P
E
V
V
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
6.6
100
93.3
100
N.A.
0
0
0
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
6.6
N.A.
26.6
100
100
100
N.A.
6.6
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
0
0
0
0
0
0
67
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% D
% Glu:
0
7
0
7
7
0
0
0
7
7
0
7
60
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
7
0
0
60
0
0
0
0
0
0
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
0
0
0
7
7
0
0
54
% I
% Lys:
47
0
0
0
0
0
0
7
7
7
0
7
0
14
7
% K
% Leu:
0
0
47
0
0
0
0
0
0
0
0
0
0
14
7
% L
% Met:
7
7
14
0
0
7
7
0
0
60
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
14
14
0
0
60
14
7
0
7
60
7
7
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
7
7
0
0
0
14
7
0
% R
% Ser:
0
47
0
0
7
0
14
7
0
0
0
7
7
0
7
% S
% Thr:
14
20
7
0
0
60
14
7
0
7
7
0
0
0
0
% T
% Val:
7
0
7
60
7
14
7
0
0
14
7
0
7
54
20
% V
% Trp:
7
0
0
0
7
7
0
0
60
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
60
7
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _