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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANLN
All Species:
17.88
Human Site:
S517
Identified Species:
35.76
UniProt:
Q9NQW6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQW6
NP_061155.2
1124
124199
S517
T
E
C
E
M
T
K
S
S
P
L
K
I
T
L
Chimpanzee
Pan troglodytes
XP_001169875
1125
124324
S518
T
E
C
E
M
T
K
S
S
P
L
K
I
T
L
Rhesus Macaque
Macaca mulatta
XP_001103129
1127
124400
S517
T
E
C
K
M
T
K
S
S
P
L
K
I
T
L
Dog
Lupus familis
XP_539518
1121
123493
E514
T
E
P
T
G
F
T
E
C
K
M
T
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K298
1121
122775
S512
T
E
S
E
M
T
K
S
S
P
L
K
I
T
L
Rat
Rattus norvegicus
XP_225479
975
107264
S410
V
D
D
E
D
I
N
S
S
K
V
I
N
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418836
1121
123757
S514
K
C
E
E
T
D
K
S
S
S
L
M
V
T
Q
Frog
Xenopus laevis
Q801E2
1116
122812
Q511
E
K
I
P
T
P
V
Q
S
Q
L
P
L
E
S
Zebra Danio
Brachydanio rerio
NP_001096146
1153
127336
V540
L
H
D
N
K
P
S
V
H
V
P
E
V
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4P1
1239
136015
A616
S
Q
T
E
D
S
S
A
G
M
C
N
G
S
L
Honey Bee
Apis mellifera
XP_624050
1031
115155
T466
K
T
D
T
E
T
G
T
E
A
E
Y
Y
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795668
1146
126808
V536
E
N
A
D
E
S
E
V
N
I
S
D
V
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.9
87.8
N.A.
80.3
70.3
N.A.
N.A.
63.6
56.4
49
N.A.
23.3
25
N.A.
24.7
Protein Similarity:
100
99.6
98.1
92.1
N.A.
87.1
77.1
N.A.
N.A.
77.3
71.7
66.3
N.A.
42.7
44.4
N.A.
43.2
P-Site Identity:
100
100
93.3
13.3
N.A.
93.3
20
N.A.
N.A.
40
13.3
0
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
40
N.A.
N.A.
46.6
26.6
13.3
N.A.
46.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
9
0
0
0
0
0
% A
% Cys:
0
9
25
0
0
0
0
0
9
0
9
0
0
0
0
% C
% Asp:
0
9
25
9
17
9
0
0
0
0
0
9
0
9
0
% D
% Glu:
17
42
9
50
17
0
9
9
9
0
9
9
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
9
0
9
0
9
0
0
0
9
0
9
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
9
0
0
0
9
0
9
34
0
9
% I
% Lys:
17
9
0
9
9
0
42
0
0
17
0
34
9
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
50
0
9
9
42
% L
% Met:
0
0
0
0
34
0
0
0
0
9
9
9
0
0
0
% M
% Asn:
0
9
0
9
0
0
9
0
9
0
0
9
9
0
9
% N
% Pro:
0
0
9
9
0
17
0
0
0
34
9
9
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
9
0
0
17
17
50
59
9
9
0
0
17
17
% S
% Thr:
42
9
9
17
17
42
9
9
0
0
0
9
0
42
0
% T
% Val:
9
0
0
0
0
0
9
17
0
9
9
0
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _