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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANLN All Species: 23.03
Human Site: S67 Identified Species: 46.06
UniProt: Q9NQW6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQW6 NP_061155.2 1124 124199 S67 S C T K P S P S K K R C S D N
Chimpanzee Pan troglodytes XP_001169875 1125 124324 S67 S C T K P S P S K K R C S D N
Rhesus Macaque Macaca mulatta XP_001103129 1127 124400 S67 S C T K P S P S K K R C S D N
Dog Lupus familis XP_539518 1121 123493 S67 S C T K P S P S K K R C S D N
Cat Felis silvestris
Mouse Mus musculus Q8K298 1121 122775 S66 E K S C T K P S P S K K R C S
Rat Rattus norvegicus XP_225479 975 107264
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418836 1121 123757 S66 K P T K P S P S K R R C S N N
Frog Xenopus laevis Q801E2 1116 122812 S67 P S S K P S P S K R R C S D N
Zebra Danio Brachydanio rerio NP_001096146 1153 127336 K67 S S K P S P F K R R C S D E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4P1 1239 136015 G99 N K E N L D M G I E I N I T T
Honey Bee Apis mellifera XP_624050 1031 115155 N34 R S P L K D A N A I L A Q A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795668 1146 126808 Q80 R L Q R L A E Q R Q V W N A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 87.8 N.A. 80.3 70.3 N.A. N.A. 63.6 56.4 49 N.A. 23.3 25 N.A. 24.7
Protein Similarity: 100 99.6 98.1 92.1 N.A. 87.1 77.1 N.A. N.A. 77.3 71.7 66.3 N.A. 42.7 44.4 N.A. 43.2
P-Site Identity: 100 100 100 100 N.A. 13.3 0 N.A. N.A. 73.3 73.3 13.3 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 33.3 0 N.A. N.A. 86.6 86.6 33.3 N.A. 13.3 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 9 0 9 0 0 9 0 17 0 % A
% Cys: 0 34 0 9 0 0 0 0 0 0 9 50 0 9 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 0 0 0 9 42 0 % D
% Glu: 9 0 9 0 0 0 9 0 0 9 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 9 0 9 0 0 % I
% Lys: 9 17 9 50 9 9 0 9 50 34 9 9 0 0 0 % K
% Leu: 0 9 0 9 17 0 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 0 0 9 0 0 0 9 9 9 59 % N
% Pro: 9 9 9 9 50 9 59 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 9 0 9 0 0 9 0 0 % Q
% Arg: 17 0 0 9 0 0 0 0 17 25 50 0 9 0 0 % R
% Ser: 42 25 17 0 9 50 0 59 0 9 0 9 50 0 17 % S
% Thr: 0 0 42 0 9 0 0 0 0 0 0 0 0 9 17 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _